Evaluation of Procedures for Production of Dust Samples for Biomedical Research

Kaya, Erol; Hogg, R.; Mutmansky, Jan M.

doi:10.1080/1047322x.1996.10389964

Cited by 7 publications

(5 citation statements)

References 7 publications

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“…Eleven building materials were chosen for determination of particle size distribution (in alphabetic order): 1) cement; 2) chalk; 3) clay; 4) gypsum; 5) hydrated lime; 6) masonry grout; 7) quartz sand; 8) sand; 9) structural lime; 10) wood grinding dust and 11) wood sawdust. Building materials used in laboratory studies were selected in accordance to in reality used building materials to ensure uniform particle size distribution as possible, their shape, composition, and other important properties (Kaya et al 1996).…”

Section: Methodsmentioning

confidence: 99%

Characterization of Particle Size Distributions of Powdery Building Material Aerosol Generated by Fluidization and Gravitation

Prasauskas¹,

Žemaitytė

Edvinas

et al. 2012

EREM

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This study aims to identify particle size distributions (PSD) of aerosol of powdery building materials commonly used in construction work (cement, chalk, clay, wood sawdust, wood grinding dust, gypsum, hydrated lime, masonry grout, quartz sand, sand and structural lime) by two aerosolization methods: fluidization and gravitation. Fluidization and gravitation methods represent industrial activities such as pneumotransportation and unloading. Both particle resuspension mechanisms have been modelled in laboratory conditions.
The particle size distributions of resuspended particulate matter from powdery building materials were rather similar identified by both fluidization and gravitation methods, with an exception of wood sawdust and sand. The PM₁₀ fraction ranged between 30% and 87%, PM_2.5from 7% to 28% and PM_1.0from 3% to 7% of the total mass of particulate matter. The highest PM₁₀/PM_total ratio was calculated for masonry grout - 0.87, and the lowest ratio for quartz sand - 0.30. The highest ratio of PM_2.5/PM_total was calculated for sand - 0.23, the lowest for quartz sand - 0.07. Substantial quantities of PM_2.5 were found to be emitted implying a potential threat to human health.

DOI: http://dx.doi.org/10.5755/j01.erem.61.3.1519

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Section: Methodsmentioning

confidence: 99%

Characterization of Particle Size Distributions of Powdery Building Material Aerosol Generated by Fluidization and Gravitation

Prasauskas¹,

Žemaitytė

Edvinas

et al. 2012

EREM

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DOI: http://dx.doi.org/10.5755/j01.erem.61.3.1519

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“…Upon receipt, the samples were coarse (ranging from 5 cm to 180 µm) and thus required milling to reduce the particle size to the size range of dust. To achieve this, a process was developed to reduce the final particle size of the population to approximately 25 µm or less applying methods defined by previous authors [12,[59][60][61] (further described in Supplementary Section S3).…”

Section: Sample Description and Preparationmentioning

confidence: 99%

Development of a SEM-EDS-XRD Protocol for the Physicochemical and Automated Mineralogical Characterisation of Coal Dust Particles

et al. 2022

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Exposure to coal dust from mining-related activities has historically been linked to several preventable but incurable respiratory diseases. Although the findings of numerous biological studies have determined that the physicochemical and mineralogical aspects of dust particles greatly influence both cytotoxic and proinflammatory pathways, robust datasets which quantitatively define these characteristics of coal dust remain limited. This study aims to develop a robust characterisation routine applicable for real-world coal dust, using an auto-SEM-EDS system. In doing so, the study addresses both the validation of the particle mineralogical scans and the quantification of a range of coal particle characteristics relevant to respiratory harm. The findings presented demonstrate the application of auto-SEM-EDS-XRD systems to analyse and report on the physicochemical and mineralogical characteristics of thousands of dust-sized particles. Furthermore, by mineralogically mapping the particles, parameters such as liberation, mineral association and elemental distribution can be computed to understand the relationships between elements and minerals in the particles, which have yet to be quantified by other studies.

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“…Dozens of varieties of dust generation/resuspension/ sampling chambers have been described in literature; previous reviews of some devices were made by Kaya et al [3] and Willeke [4] for biomedical applications and by Cowherd and Grelinger [5] for wind erosion and fugitive dust research. Dust generation and dustiness testing instruments have been designed for a wide variety of purposes: for simulating indoor air in dusty manufacturing facilities [6]; for industrial process control [7]; in the pharmaceutical industry (where the objective may be to develop devices such as dry-powder inhalers that maximize the concentration of fine aerosols, for optimal delivery into the respiratory tract) [8][9][10][11][12][13]; exposing laboratory animals to mineral aerosols for respiratory disease studies [14,15]; preparing samples for chemical analysis [16]; measuring ecophysiological effects of dust accumulation on leaves [17]; simulating solid particle penetration into buildings [18,19]; or even to predict mineral dust accumulation or dispersion on other planets or outer space [20].…”

Section: A Review Of Laboratory Dust Aerosol Generation Systemsmentioning

confidence: 99%

“…However, dust generated in a laboratory setting should be similar in particle size, shape and composition to ambient dust aerosols or at least some component of them, and free of contamination resulting from the (dust generation) process [3]. This paper documents and categorizes the many devices used by various research groups to generate dry powder aerosols in the laboratory with applications to geological dust generation and dustiness testing.…”

Section: Introductionmentioning

confidence: 99%