Evaluation of pregnancy and foaling rates after reduction of twin pregnancy via transvaginal ultrasound-guided aspiration in mares

Klewitz, Jutta; Krekeler, Natali; Ortgies, Florian; Heberling, A; Linke, Corinna; Sieme, Harald

doi:10.2460/javma.242.4.527

Cited by 12 publications

(33 citation statements)

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“…In the current study, TUA success rates showed no significant differences according to the gestational periods evaluated. This is in agreement with Klewitz et al (13) for data evaluated up to 4 weeks after TUA. However, the authors found that live foaling rate was significantly reduced when TUA was performed after day 42 (13).…”

Section: Discussionsupporting

confidence: 93%

“…This is in agreement with Klewitz et al (13) for data evaluated up to 4 weeks after TUA. However, the authors found that live foaling rate was significantly reduced when TUA was performed after day 42 (13). Several other studies exist indicating that puncture of unicornually located twins is significantly more successful if done before day 35 of gestation (5,11).…”

Section: Discussionsupporting

confidence: 93%

“…In previous studies on reduction of twin pregnancies by transvaginal ultrasound-guided aspiration, different definitions of success of TUA procedures have been used, which needs to be considered, when comparing data. Results described in the present study are comparable with those of Klewitz et al (13). These authors found a 73 % positive outcome (for 44 mares being treated), when success was defined as an ultrasonographically confirmed pregnancy with a viable conceptus 5-7 days after TUA.…”

Section: Discussionsupporting

confidence: 90%

“…In the present study, 88 mares underwent TUA with a 74 % success rate according to the criteria mentioned before. Furthermore, with re-examination 3-4 weeks after TUA, Klewitz et al (13) found 75 % (18 of 24) positive outcome. In comparison, out of 88 mares, 65 mares showed a viable singleton pregnancy in the first follow-up (5-7 days) and 59 mares in the second (4 weeks after TUA) in the present study.…”

Section: Discussionmentioning

confidence: 97%

“…Most of these studies included less than 20 TUAs. Recent studies which included large numbers, showed live foaling rates of 33 and 49 % (12,13). Higher success rates were achieved if TUA was performed before day 35 (40 and 57 %) compared to TUAs after day 35 (26 and 30 %) of pregnancy.…”

Section: Introductionmentioning

confidence: 99%

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Effects of mares’ age and day of gestation on efficacy of transvaginal ultrasound-guided twin reduction

Rau¹,

Tiedemann²,

Sielhorst³

et al. 2018

Tierarztl Prax Ausg G

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Summary Objective: Transvaginal ultrasound-guided aspiration (TUA) is a procedure which can be used for the reduction of twins post-fixation in the mare. The aim of this study was to evaluate the effect of the age of mares and the day of gestation on the outcome of TUA treatment. Material and methods: In 88 mares, diagnosed pregnant with twins, TUA of the yolk sac or allantoic fluid was performed between day 30 and 62 of gestation. Mares were aged 3–22 years. Ultrasonographic examination for a viable singleton pregnancy was performed by referring veterinarians 5–7 days and 4 weeks after TUA. Based on reported findings, effects of age and day of gestation on pregnancy rates were evaluated. Results: Four weeks after TUA, 67% of the cases resulted in a viable singleton pregnancy. Five to 7 days after TUA treatment, the success rate was 74%. The gestational period did not affect the outcome, irrespective of the age of the mare. In contrast, success rates decreased with increasing age of the mares (84% ≤ 7 years vs. 67% 8–14 years vs. 57% ≥ 15 years). In mares aged 8–14 years, a decrease in singleton pregnancies was observed, if TUA was performed after day 35 of gestation. Success rates were slightly higher, if twin vesicles were localized within separate uterine horns (73%) as compared to the same horn (66%). Differences in singleton pregnancy rates were not statistically significant (p > 0.05). Conclusions and clinical relevance: TUA was found to be an effective procedure for reduction of twin pregnancies performed at days 30–62 of gestation. Success rates for singleton pregnancies were high for young mares ≤ 7 years old (84%) and middle aged mares treated before day 36 of pregnancy (74%). Duration of pregnancy at the time of TUA did not have a major impact on the outcome. Nevertheless, the procedure should optimally be performed around days 32–35 of pregnancy to allow for the possibility of natural reduction before treatment and rebreeding in case of a total pregnancy loss after TUA.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Effects of mares’ age and day of gestation on efficacy of transvaginal ultrasound-guided twin reduction

Rau¹,

Tiedemann²,

Sielhorst³

et al. 2018

Tierarztl Prax Ausg G

Self Cite

View full text Add to dashboard Cite

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Twin Reduction

Wolfsdorf

2021

Equine Reproductive Procedures

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Highlights of recent clinically relevant papers

Wright¹

2013

Equine Veterinary Education

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colleagues in the USA, Canada and Australia have recently published the findings of their retrospective case series which aimed to identify epidemiological trends in cutaneous neoplasms affecting equids in central North America and compare them with previously reported trends.A total of 3351 cutaneous biopsy specimens from 3272 equids with a neoplastic diagnosis were examined. Diagnostic reports from 2 diagnostic laboratories (Colorado State University and Prairie Diagnostic Services Inc) were reviewed for frequency of specific lesions and epidemiological trends. Variables included in analyses (if known) were age, sex, breed, geographic location, date of diagnosis, location of neoplasm on the body and presence or absence of ulceration.Sarcoid, squamous cell carcinoma (SCC) and melanoma were the 3 most common tumours diagnosed. Tumours associated with UV radiation (SCC, SCC in situ, haemangioma, haemangiosarcoma) were 2.3 times as common in biopsy specimens received by Colorado State University than in specimens received by Prairie Diagnostic Services Inc. Appaloosa horses and American Paint horses, respectively, were 7.2 and 4.4 times as likely as other breeds to have tumours associated with UV radiation. Thoroughbreds were predisposed to cutaneous lymphoma, whereas Arabians were more likely to have melanomas. Draught and pony breeds were 3.1 times as likely as other breeds to have benign soft tissue tumours. Morgans and pony breeds more commonly had basal cell tumours. Tumours in the perianal region were significantly more likely to be SCC or melanoma while tumours on the limbs were more likely to be giant cell tumour of soft parts. The authors concluded that signalment, anatomic location of the mass, and geographic location of the horse can be used to help equine practitioners formulate differential diagnoses for cutaneous masses. Further research is necessary to identify the biological basis for the development of many equine cutaneous neoplasms. Antimicrobial resistanceAdele Williams and colleagues in the UK have recently published the findings of their study to determine whether hospitalisation of horses leads to increased antimicrobial resistance in equine faecal Escherichia coli isolates.Escherichia coli were cultured from faecal samples of horses on admission and after 7 days of hospitalisation; antimicrobial susceptibility was determined for 8 antimicrobial agents. Resistance profiles of E. coli isolates were grouped into clusters, which were analysed to determine resistance patterns. Resistance to 7/8 antimicrobial agents and multi-drug resistance (MDR; resistance to Ն3 antimicrobial classes) were significantly higher after 7 days of hospitalisation. Forty-eight resistance profiles were identified; 15/48 were present on Day 0 only, 16/48 on Day 7 only and 17/48 at both times of sampling. There was a significant association between Day 7 profiles and resistance detected to an increased number of antimicrobial agents. Hospitalisation of horses for 7 days resulted in alterations in equine faecal E. coli an...

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Evaluation of pregnancy and foaling rates after reduction of twin pregnancy via transvaginal ultrasound-guided aspiration in mares

Abstract: TUA was effective for reduction of twin pregnancy in mares, with best results achieved before gestational day 43.

Cited by 12 publications

References 21 publications

Effects of mares’ age and day of gestation on efficacy of transvaginal ultrasound-guided twin reduction

Effects of mares’ age and day of gestation on efficacy of transvaginal ultrasound-guided twin reduction

Twin Reduction

Highlights of recent clinically relevant papers

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