Evaluation of post-obturation pain in single-visit endodontic treatment after pre-medication with oral anti-inflammatory and antibiotics. An in-vivo study

Abstract

The objective of the study was to evaluate post-obturation pain on the 1 st , 3 rd , and 7 th days on single-visit endodontic treatment after taking antibiotics and anti-inflammatory drugs.Methods: Permanent molars were managed with single-visit root canal treatment after pre-medication in 80 patients. Patients were randomly assigned to four groups (n = 20); Group-1; amoxicillin (500 mg) + clavulanic acid (125 mg), Group-2; aceclofenac (100 mg) + paracetamol (325 mg); Group-3; anti-inflammatory and antibiotics; and Group-4; without pre-medication. Medications were administered 1 h before treatment. Patients filled a visual analog scale form to rate their pain at 1 st , 3 rd , and 7 th days. Kruskal-Wallis test was used to obtain mean rank and the level of significance was set at 0.05.