Evaluation of portal hypertension and prognosis of patients with HIV/HCV co-infection through comtaminated blood product

光寿, 高槻; 晋, 江口; 明彦, 曽山; 兼松隆之,; 一彦, 中尾; 琢磨, 白阪; 政弘, 山本; 博之, 潟永; 夏夫, 立川; 有希, 釘山; 弘, 八橋; 隆文, 市田; 典宏, 國土

doi:10.2957/kanzo.53.586

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…10 In the present study, co-infected patients with a platelet count less than 150,000 µL had an especially poor prognosis, with a shorter survival than mono-infected patients. Our results should be taken into account to establish a therapeutic strategy, while also considering the appropriate timing of liver transplantation in HIV/HCV co-infected patients.…”

Section: Eguchi Et Almentioning

confidence: 45%

Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan

Eguchi

Takatsuki

Soyama

et al. 2014

Transplantation Proceedings

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Background: As the survival of HIV-infected individuals has improved due to the widespread use of antiretroviral therapy, the mortality rate due to HCV-related liver disease has increased in HIV/HCV co-infected patients. Aim: 1. To establish the appropriate therapeutic strategy for HIV/HCV co-infected patients by evaluating the liver function, including the hepatic functional reserve and portal hypertension. 2. To investigate the prognosis of HIV/HCV co-infected patients in Japan. Patients and

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Section: Eguchi Et Almentioning

confidence: 45%

Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan

Eguchi

Takatsuki

Soyama

et al. 2014

Transplantation Proceedings

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“…Even HIV/HCV co‐infected liver cirrhotic patients with Child–Pugh class A can be listed for LT as “point 3” because of NCPH nature. Also co‐infected patients with Child–Pugh class B and C can be listed as “point 6” and “point 8” based on the data from our HIV/AIDS project team of the Ministry of Health, Labor, and Welfare of Japan, and world literatures . It is basically considered for previous victims of contaminated blood products for hemophilia.…”

Section: Current Results Of Lt For Hiv/hcv Co‐infected Patients In 2013mentioning

confidence: 99%

Liver transplantation for patients with human immunodeficiency virus and hepatitis C virus co‐infection: update in 2013

Eguchi

Takatsuki

Kuroki

2013

J Hepato Biliary Pancreat

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Because of the progress of anti-retroviral therapy (ART) for human immunodeficiency virus (HIV), mortality due to opportunistic infection resulting in AIDS has been remarkably reduced. However, meanwhile, half of those patients have died of end-stage liver cirrhosis due to hepatitis C virus (HCV) with liver cirrhosis and early occurrence of hepatocellular carcinoma. Recently, in 2013, noncirrhotic portal hypertension due to ART drugs or still unknown mechanisms have become problematic with early progression of the disease in this patient population. Liver transplantation (LT) could be one treatment of choice in such cases, but the indications for LT perioperative management, including both HIV and HCV treatments and immunosuppression, are still challenging. In this review, we update the literature on HIV/HCV co-infection and LT as well as recent effort for modifying allocation system for those patients.

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Current issues and problems of deceased donor liver transplantation in Japan

Ichida

Genda

Hirano³

2015

Acta hepatologica Japonica

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Evaluation of portal hypertension and prognosis of patients with HIV/HCV co-infection through comtaminated blood product

Cited by 3 publications

References 11 publications

Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan

Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan

Liver transplantation for patients with human immunodeficiency virus and hepatitis C virus co‐infection: update in 2013

Current issues and problems of deceased donor liver transplantation in Japan

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