Evaluation of Poorly Differentiated Head and Neck Neoplasms: Immunocytochemistry Techniques

Undifferentiated head and neck tumors: the contribution of immunohistochemical technique to differential diagnosis

“…However,there are only a few references in the literature to the immunohistochemical technique applied to the identification of undifferentiated head and neck tumors. [8][9][10][11] In this retrospective analysis, we evaluated the occurrence of undifferentiated head and neck tumors in our service and the way in which they were distributed, according to cell pattern, patient's age and tumor localization.…”

Poorly-Differentiated Laryngeal Malignancies

“…Such a multiparameter ap proach has proved of great assistance to con ventional tumour diagnosis by pattern recog nition alone. The identification of various diagnostic, though non-specific [3], antigenic substances in individual cells by means of monoclonal antibodies has led to a more pre cise diagnosis of a tumour which could be defined according to cell type. Important de cisions on the choice of surgery, radiothera py, chemotherapy or laser therapy depend on this.…”