Evaluation of polyherbal formulation in broilers fed high energy diet: Implications on zootechnical parameters, fat accretion, and serum L-carnitine levels

Abstract

Objective: The current broiler trial was planned to assess the effects of Kolin Plus™, a polyherbal formulation (PHF), on performance, protein and fat accretion, and serum L-carnitine (LC) levels in broilers fed a high-energy diet (HED). Materials and Methods: A total of 500 1-day-old Cobb 430 male chicks were assigned to 5 treatment groups consisting of 10 replicates, with 10 birds in each replicate ( n = 100). Group G1 was a negative control fed HED, and group G2, a positive control supplemented with synthetic choline chloride (SCC) 1,500 gm/ton in HED. Groups G3, G4, and G5 were supplemented with PHF in HED at 400, 500, and 750 gm/ton feed, respectively (PHF400, PHF500, and PHF750). Results: The PHF produced a dose-dependent numerical improvement in body weight, feed conversion ratio, livability, and the European Production Index. There were no changes in carcass nitrogen and protein accretion, whereas a statistically significant decrease ( p < 0.05) in carcass fat and fat accretion was observed in the SCC and PHF groups. Moreover, PHF showed a significant increase in serum LC levels. Conclusion: Kolin Plus™ improves performance parameters akin to SCC by improving fat metabolism and mobilization by enhancing serum LC levels and restoring normal fat accretion.

Efficacy and Significance of Bio Choline as Choline Source in Poultry

“…The building and maintaining of cell structure, and formation of acetylcholine are treated as structural roles. While the lipid metabolism and that of being a methyl group donor come under the functional role [3].…”

Choline supplementation: Impact on broiler chicken performance, steatosis, and economic viability from from 1 to 42 days

“…Typically, choline plays a significant role in many important metabolic pathways, being crucial for the structural maintenance of cell membranes and organelles, acting as a constituent of phospholipids [1,2] synthesis of methionine from homocysteine as a labile methyl donor; and a precursor molecule for the formation of acetylcholine in the nervous system. In addition, the choline is a component of very-low-density lipoproteins (VLDL) which involves in triglyceride transport out of the liver and thereby reduces the accumulation of fat in the liver [3][4][5][6]. It also inhibits the fatty acid synthesis by downregulating fatty acid synthase gene expression as well as attenuating its activity [7,8].…”