Evaluation of Plasma Skin Regeneration Technology in Low-Energy Full-Facial Rejuvenation

Bogle, Melissa A.; Arndt, Kenneth A.; Dover, Jeffrey S.

doi:10.1001/archderm.143.2.168

Cited by 139 publications

(121 citation statements)

References 7 publications

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“…Applying non-thermal plasma for cancer treatment is described in detail in the next chapter. Bogle et al (2007) have developed plasma skin regenerative technology for facial rejuvenation (see Fig. 43).…”

Section: Other Applications Of Plasma Medicinementioning

confidence: 99%

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State of the art in medical applications using non-thermal atmospheric pressure plasma

Tanaka

Ishikawa

Mizuno

et al. 2017

Rev. Mod. Plasma Phys.

105

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Plasma medical science is a novel interdisciplinary field that combines studies on plasma science and medical science, with the anticipation that understanding the scientific principles governing plasma medical science will lead to innovations in the field. Non-thermal atmospheric pressure plasma has been used for medical treatments, such as for cancer, blood coagulation, and wound healing. The interactions that occur between plasma and cells/tissues have been analyzed extensively. Direct and indirect treatment of cells with plasma has broadened the applications of non-thermal atmospheric pressure plasma in medicine. Examples of indirect treatment include plasma-assisted immune-therapy and plasma-activated medium. Controlling intracellular redox balance may be key in plasma cancer treatment. Animal studies are required to test the effectiveness and safety of these treatments for future clinical applications.Keywords Plasma medical science Á Plasma cancer therapy Á Plasma-activated medium (PAM) Á Reactive oxygen species (ROS) Abbreviations ALKAnaplastic lymphoma kinase AMD Age-related macular degeneration APF Aminophenyl Fluorescein CNV

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Section: Other Applications Of Plasma Medicinementioning

confidence: 99%

“…Initial clinical trials of plasma cancer treatments have been reported (Metelmann et al Fig. 43 Rejuvenation using plasma skin regeneration technology (Bogle et al 2007). Plasma skin regeneration procedure performed in a paintbrush fashion, holding the handpiece approximately 5 mm from the skin surface.…”

Section: Direct Treatmentmentioning

confidence: 99%

State of the art in medical applications using non-thermal atmospheric pressure plasma

Tanaka

Ishikawa

Mizuno

et al. 2017

Rev. Mod. Plasma Phys.

105

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“…Denaturation of collagen and other proteins in the dermis following the thermal effect of plasma induces clinically observed, immediate tissue contraction [1] . Cascade of neo-collagenization has been stimulated through thermal disruption of dermal solar elastosis, fibroblasts activation, and migration from the deeper dermis and cytokine release [1,6,7] . Plasma is more uniform than ablative resurfacing lasers, including carbon dioxide (CO 2 ) resurfacing laser, since it does not depend on the interaction with a specific target [1] .…”

Section: Histopathological Aspects Of Plasmamentioning

confidence: 99%

“…Plasma is more uniform than ablative resurfacing lasers, including carbon dioxide (CO 2 ) resurfacing laser, since it does not depend on the interaction with a specific target [1] . Regarding the level of energy of plasma and tissue shedding, high-energy plasma induces shedding in epidermis and upper dermis, whereas low-energy plasma induces shedding in only the upper part of tum corneum [6,7] .…”

Section: Histopathological Aspects Of Plasmamentioning

confidence: 99%

Plasma application in aesthetic medicine: Clinical and physical aspects

Pourazizi

Abtahi‐Naeini

2017

J Surg Dermatol

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“…An in vivo study showed that PSR could consistently achieve thermal injury into the papillary dermis resulting in collagen remodeling without permanent pigmentary or textural irregularities [5]. Following this, multiple sites demonstrated that facial rhytides could be safely and effectively improved with this device [3,6]. Furthermore, PSR has been shown to remove benign skin lesions with similar efficacy and low complication rate as the carbon dioxide (CO 2 ) laser [4].…”

Section: Introductionmentioning

confidence: 99%

Treatment of acne scars using the plasma skin regeneration (PSR) system

et al. 2008

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Background and Objectives: Acne scarring is a common and difficult to treat condition. The plasma skin regeneration (PSR) system is a novel device that causes delayed ablation of the epidermis and controlled thermal modification to the underlying dermis. PSR has previously been shown to be a safe and effective treatment for facial rhytides and benign skin lesions. In this study, we investigated the safety and efficacy of single-treatment, highenergy, double-pass PSR for the treatment of acne scarring. Study Design/Materials and Methods: Ten patients with acne scarring and Fitzpatrick skin types I-III were included in the study. All patients underwent a single PSR treatment with two high-energy passes (3.5-4.0 J). Treatments were performed in an outpatient clinic setting. Nine patients completed 6 months of follow-up. Improvement was determined by patient questionnaires and physician evaluation of digital photographs taken prior to treatment and at 3 and 6 months post-treatment. Results: On average, patients reported 34% improvement in their acne scarring at 3 months and 33% improvement at 6 months. Blinded physician ratings of patient photos demonstrated 19% improvement at 3 months and 34% at 6 months. Re-epithelialization was complete by 4-6 days after treatment, and no serious adverse events were encountered. Conclusion: PSR appears to provide a safe and effective single treatment, minimal downtime alternative for the treatment of acne scarring. Additional studies are warranted to further demonstrate the safety and efficacy of this device.

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Evaluation of Plasma Skin Regeneration Technology in Low-Energy Full-Facial Rejuvenation

Cited by 139 publications

References 7 publications

State of the art in medical applications using non-thermal atmospheric pressure plasma

State of the art in medical applications using non-thermal atmospheric pressure plasma

Plasma application in aesthetic medicine: Clinical and physical aspects

Treatment of acne scars using the plasma skin regeneration (PSR) system

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