Evaluation of Phytochemicals, Total Phenols, Antioxidant and Anthelmintic Activity of Hot Water Extracts of Cuminum Cyminum Seeds

Abstract

In traditional medicine, cumin seeds were used as stomachic, diuretic, carminative, stimulant, astringent and abortifacient properties. Its seeds are used commonly for herbal drink preparation in Kerala and consumed as part of diet. The present study was carried out to investigate the phytochemical profile, total phenol content, antioxidant and anthelmintic activity of hot water extracts of seeds of Cuminum cyminum. Phytochemical analysis showed the presence of saponins, steroids, alkaloids, phenols and tannins. The total phenol content in 5 µg/ µl hot water extract is 50 µg/ µl phenol expressed as catechol equivalent. The radical scavenging potential showed dose dependent increase on increasing the concentration of cumin seed extracts 1-5 µg. IC50 value of seeds was 1.82 µg/µl. Anthelmintic activity also showed dose dependant increase.