Evaluation of Phenolic Content and Antioxidant Potency in Various Parts of Cassia auriculata L.: A Traditionally Valued Plant

Abstract

Presence of polyphenolic content in various part of the plant exhibit wide pharmacological activities including antioxidant activity. The present study was designed to evaluate the phenolic contents (total phenols, flavonoid and tannins) and antioxidant properties of ethanolic extracts of flower, leaf, pod, bark and root obtained from Cassia auriculata. Ethanolic extracts of various parts of C. auriculata obtained by sonication extraction techniques are studied for their phenolic contents and DPPH (2,2-diphenyl-1-picrylhydrazine) radical scavenging assay as well as total antioxidant assays using UV visible spectrophotometer. Among the various parts of the plant studied, bark showed significant content of phenolics, flavonoids and tannins followed by the root, leaf, flower and pod. Even bark extract exhibited highest antioxidant capacity in DPPH assay followed by root, leaf, flower and pod with a value of 766.7, 679.3, 644.9, 572.5 and 474.7 mg vitamin C equivalent antioxidant capacity (mg VCEAC)/sample, respectively. In addition, mg VCEAC values obtained from the total antioxidant assay was in the increasing order of bark > root > leaf > flower > pod. Moreover, a strong correlation was also found between phenolic contents and antioxidant values indicating their influence in the found antioxidant activity, hence the bark extract can be employed as an ideal candidate for herbal based pharmaceutical product. Results of the present study also emphasize variation in the chemical composition as well as biological activity ensuring the importance of proper selection of particular part of the plant to evaluate their therapeutic potency.

Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

“…Five groups were fed for 4 weeks with a diet consisting of 50% Corn Starch, 11.25% Rice Powder, 01% vegetable oil, 10% egg white, 08% fish meal, 19% Cellulose, 0.125% mineral complex, 0.125% vitamin Complex and 0.50% Salt [19, 20]. For induction of hypercholesterolemia (HC), 1% of cholesterol was added in the feed of rats.…”

Hepatoprotective evaluation of tinospora cordifolia against drug induced hepatotoxicity

“…Phytochemical studies of Tinosporacordifolia leaves disclosed the presence of pharmacologically active families of a molecule, that includedterpenoides, tannins,cardiac glycosides, terpenes, saponins ,anthroquinones, inorganic elements [5,6]. Extracts of these plants were reported to have antifungal, antiviral [7,8]antibacterial, antihelminthic [9,10], antispasmodic, analgesic, antipyretic, anti-inflammatory [11,12]and hepatoprotective properties in humans and experimental models [13,14].Verma, et al (2010) reported the effect of methanolic extract of Tinosporacordifoliafor to manage thealloxan-induced diabetic rats [15],antiallergic, anti-inflammatory, and anti-lipid peroxiding properties have been reported by Sreejith et al [16]. The goal of this study is to see if the Methanolic extract of Tinosporacordifoliaroot has any hepatoprotective properties in albino wistar rats.…”

Review on ethnobotany, phytochemistry, and pharmacological properties of Cassia auriculata

“…Further disorders like leprosy, ulcer, eye irritation, skin disorders. 7,8 The plant is been reported for their antidiabetic, 9 antioxidant, 10 antibacterial, 11 hepatoprotective, 12 nephroprotective, 13 anticancer, 14 anti-inflammatory, 15 anti-microbial 16 and anti-hyperlipidemic activities. 17 The present review was written to provide the overview of this plant on its various pharmacological properties, its traditional and folklore use and phytochemical nature.…”