Evaluation of pH and calcium ion release of Acroseal sealer in comparison with Apexit and Sealapex sealers

Eldeniz, Ayçe Ünverdi; Erdemir, Ali; Kurtoğlu, Firuze; Esener, Timur

doi:10.1016/j.tripleo.2006.10.018

Cited by 44 publications

(56 citation statements)

References 35 publications

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“…36 Although Acroseal has a long setting time, 12 its calcium release was inferior to that with Sealapex because of the relative insolubility of its epoxy base. This finding illustrates the need for calcium hydroxide-based sealers to be minimally soluble and liberate hydroxyl and calcium ions, 35 which explains the absence of mineralization observed in this study.…”

Section: Discussionsupporting

confidence: 60%

“…27,28 Endodontic sealers containing calcium oxide have been suggested as obturating materials because of their capacity to dissociate into calcium and hydroxyl ions, resulting in a higher pH that favors repair and induces mineralized tissue formation. 13,26,35,39 The setting time could favor a calcium ion release that generally occurs before the setting of materials. 36 Although Acroseal has a long setting time, 12 its calcium release was inferior to that with Sealapex because of the relative insolubility of its epoxy base.…”

Section: Discussionmentioning

confidence: 99%

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Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers

et al. 2016

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Obturation of the root canal system aims to fill empty spaces, promoting hermetic sealing and preventing bacterial activity in periapical tissues. This should provide optimal conditions for repair, stimulating the process of biomineralization. An endodontic sealer should be biocompatible once it is in direct contact with periapical tissues. The aim of this study was to evaluate the rat subcutaneous tissue response to implanted polyethylene tubes filled with Smartpaste Bio, Acroseal, and Sealapex and investigate mineralization ability of these endodontic sealers. Forty Wistar rats were assigned to the three sealers groups and control group, (n = 10 animals/group) and received subcutaneous implants containing the test sealers, and the control group were implanted with empty tubes. After days 7, 15, 30, and 60, animals were euthanized and polyethylene tubes were removed with the surrounding tissues. Inflammatory infiltrate and thickness of the fibrous capsule were histologically evaluated. Mineralization was analyzed by Von Kossa staining and polarized light. Data were tabulated and analyzed via Kruskal-Wallis and Dunn's test. All tested materials induced a moderate inflammatory reaction in the initial periods. Smartpaste Bio induced the mildest inflammatory reactions after day 15. No difference was observed among groups after days 30 or 60. Von Kossa-positive staining and birefringent structures observed under polarized light revealed a larger mineralization area in Sealapex-treated animals followed by Smartpaste Bio-treated animals. At the end of the experiment, all tested sealers were found to be biocompatible. All sealers induced biomineralization, except Acroseal, which induced a mild tissue reaction.

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Section: Discussionsupporting

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers

et al. 2016

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“…It has good radiopacity, 16 excellent film thickness, 17 however, it presents a lower calcium ion release and pH compared with Sealapex. 18 AH Plus is an epoxybis-phenol resin that comes in two tubes of epoxide paste and amine paste. Endoflas FS is iodoform incorporated zinc oxide eugenol sealer that also contains calcium hydroxide.…”

Section: Introductionmentioning

confidence: 99%

A comparative study of apical microleakage of different root canal sealers by apical dye penetration

Ayer

Manandhar

Agrawal

et al. 2017

Bangladesh J Med Sci

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Abstract:Objective: This study was designed to compare the level of apical microleakage of root canal sealers; Acroseal, AH Plus, Endoflas FS and Endomethasone N, with laterally condensed gutta percha by level of apical dye penetration. Materials and Methods: Freshly extracted sixty permanent maxillary anterior teeth were divided randomly into four groups. Shaping and cleaning of teeth was done followed by obturation with gutta percha and four different root canal sealers. Samples were immersed in 2% methylene blue dye solution in individual dappen dish and stored in the solution for 30 days. The roots were split longitudinally with a chisel in two halves and observed under stereomicroscope. Apical microleakage measured from the apex to the most coronal extent of dye penetration. Results: Minimum microleakage was observed with AH Plus with mean value 2.140 mm, standard deviation 0.817. The maximum microleakage was observed with Endomethasone N with mean value 3.858 mm, standard deviation 1.840. There was no statistically significant difference in microleakage between Acroseal, AH Plus, and Endoflas FS. Endomethasone N showed highest level of microleakage than other three groups under the test condition, which was statistically significant. Conclusion: The microleakage was the lowest for the AH Plus and increased in the following order, Endoflas FS, Acroseal, Endomethasone N.

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“…However, Acroseal showed the least amount of calcium and hydroxyl ion release, due to the relative insolubility of its compounds. 9 The low solubility of Acroseal can explain its difference from Sealapex, 28 although both are hydroxide-based sealers, and showed late antimicrobial activity, suggesting that Acroseal needs a longer time to release hydroxyl ions.…”

Section: Discussionmentioning

confidence: 99%

“…1 Moreover, calcium ions can react with carbon dioxide and reduce the breathing source of anaerobic bacteria. 9 AH Plus is a sealer with antimicrobial activity against F. nucleatum, P. gingivalis, 10 and E. faecalis.…”

Section: E Faecalis Is Also Ablementioning

confidence: 99%

Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm

et al. 2016

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Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm Abstract: Enterococcus faecalis are gram positive bacteria that can mostly resist endodontic therapy, inducing persistent infection in the root canal system. Endodontic sealers with antimicrobial activity may help eliminate residual microorganisms that survive endodontic treatment. The present study aimed at comparing the antimicrobial activity of Acroseal, Sealapex and AH Plus endodontic sealers in an in vitro biofilm model. Bovine dentin specimens (144) were prepared, and twelve blocks for each sealer and each experimental time point (2, 7 and 14 days) were placed and left in contact with plates containing inoculum of E. faecalis (ATCC 51299), to induce biofilm formation. After 14 days, the samples were transferred to another plate with test sealers and kept at 37°C and 5% CO 2 for 2, 7 and 14 days. The specimens without sealers were used as a control for each period. The samples were agitated in a sonicator after each experiment. The suspensions were agitated in a vortex mixer, serially diluted in saline, and triple plated onto m-Enterococcus agar. Colonyforming units were counted, and the data were statistically analyzed using ANOVA, Shapiro-Wilk and Kruskal-Wallis one-way tests (p < 0.05) to determine antimicrobial potential. Sealapex showed significant differences at all the experimental time points, in comparison with all the other groups. AH Plus and Acroseal showed antimicrobial activity only on the 14 th experimental day. Neither of the sealers tested were able to completely eliminate the biofilm. Sealapex showed the highest antimicrobial activity in all the experimental periods. The antimicrobial activity of all the sealers analyzed increased over time.

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Evaluation of pH and calcium ion release of Acroseal sealer in comparison with Apexit and Sealapex sealers

Cited by 44 publications

References 35 publications

Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers

Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers

A comparative study of apical microleakage of different root canal sealers by apical dye penetration

Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm

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