Evaluation of parathyroid hormon ıncrease after parathyroidectomy in primary hyperparathyroidism

Abstract

In this study, we tried to evaluate retrospectively high levels of parathyroid hormone in patients who received parathyroidectomy due to primary hyperparathyroidism in the light of the literature search. Methods: In this study, 121 patients who underwent surgery for primary hyperparathyroidism between September 2015 and December 2017 were retrospectively evaluated, according to gender, preoperative calcium and PTH levels, postoperative calcium and PTH levels, diagnosis, histopathological results, type of surgery, follow-up time and recurrence. We excluded patients who were unreachable. Results: Mean age was 54.83±12.56 (26-82). One hundred three patients were female (85.1%). One hundred nineteen patients were diagnosed (98.4%) as adenoma, whereas two patients were diagnosed as (1.6%) hyperplasia. According to histopathological results, 103 (85.1%) adenoma, four (3.3%) carcinoma, four (3.3%) hyperplasia and 10 (8.2%) adenoma and papillary carcinoma of the thyroid were found. Preoperative mean PTH value was 301.9±470 pg/ml (79-3674 pg/ml). Preoperative mean calcium level was 10.