Evaluation of Outcome of Intravenous Catheter-related  Infections in Critically Ill Patients

Rello, Jordi; Ochagavía, A.; Sabanes, Elena; Figuls, Marta Roqué i; Mariscal, Dolors; Reynaga, Esteban; Vallès, Jordi

doi:10.1164/ajrccm.162.3.9911093

Cited by 316 publications

(188 citation statements)

References 18 publications

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“…No excess mortality 24,25,[32][33][34][35] and dramatic mortality and 103 nonexposed subjects. Table 2 summarizes the characteristics of the exposed and nonexposed groups.…”

Section: Discussionmentioning

confidence: 99%

Morbidity and Mortality of Bloodstream Infections in Patients With Severe Burn Injury

Brusselaers¹,

Monstrey²,

snoeij³

et al. 2010

American Journal of Critical Care

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“…No excess mortality 24,25,[32][33][34][35] and dramatic mortality and 103 nonexposed subjects. Table 2 summarizes the characteristics of the exposed and nonexposed groups.…”

Section: Discussionmentioning

confidence: 99%

Morbidity and Mortality of Bloodstream Infections in Patients With Severe Burn Injury

Brusselaers¹,

Monstrey²,

snoeij³

et al. 2010

American Journal of Critical Care

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“…Recent studies suggest that if adjustments are made for the patient's health state before infection, then the attributable mortality risk may be smaller than is currently assumed. 89 In any good quality economic evaluation the reference case rate will be varied within the sensitivity analysis.…”

Section: Attributable Mortalitymentioning

confidence: 99%

“…Anticipated savings are related to the number of CVCs inserted in specific patient groups per year. Only the results of the Spanish study appear to be somewhat cautious; Rello and colleagues 89 conclude that catheter-related infections lead to increased costs and that the potential economic benefits of new techniques to prevent intravascular catheter-related infections need to be explored.…”

Section: Potential Savings From Preventing Crbsismentioning

confidence: 99%

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

Hockenhull¹,

Dwan²,

Boland³

et al. 2008

Health Technol Assess

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“…If the average rate of CVC-associated BSIs is 5.3 per 1,000 catheter days in the ICU [3], approximately 80,000 CVC-associated BSIs occur in ICUs each year in the United States. The attributable mortality for these BSIs has ranged from no increase in mortality in studies that controlled for severity of illness [4][5][6], to 35% increase in mortality in prospective studies that did not use this control [7,8]. Thus, the attributable mortality remains unclear.…”

Section: Introductionmentioning

confidence: 99%

“…Thus, the attributable mortality remains unclear. The attributable cost per infection is an estimated $34,508-$56,000 [5,9], and the annual cost of caring for patients with CVC-associated BSIs ranges from $296 million to $2.3 billion [10].…”

Section: Introductionmentioning

confidence: 99%

Guidelines for the prevention of intravascular catheter-related infections

O’Grady¹,

Alexander²,

Dellinger³

et al. 2002

American Journal of Infection Control

635

843

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These guidelines have been developed for practitioners who insert catheters and for persons responsible for surveillance and control of infections in hospital, outpatient, and home health-care settings. This report was prepared by a working group comprising members from professional organizations representing the disciplines of critical care medicine, infectious diseases, health-care infection control, surgery, anesthesiology, interventional radiology, pulmonary medicine, pediatric medicine, and nursing. The These guidelines are intended to provide evidencebased recommendations for preventing catheter-related infections. Major areas of emphasis include 1) educating and training health-care providers who insert and maintain catheters; 2) using maximal sterile barrier precautions during central venous catheter insertion; 3) using a 2% chlorhexidine preparation for skin antisepsis; 4) avoiding routine replacement of central venous catheters as a strategy to prevent infection; and 5) using antiseptic/antibiotic impregnated short-term central venous catheters if the rate of infection is high despite adherence to other strategies (i.e., education and training, maximal sterile barrier precautions, and 2% chlorhexidine for skin antisepsis). These guidelines also identify performance indicators that can be used locally by health-care institutions or organizations to monitor their success in implementing these evidence-based recommendations.

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Evaluation of Outcome of Intravenous Catheter-related Infections in Critically Ill Patients

Cited by 316 publications

References 18 publications

Morbidity and Mortality of Bloodstream Infections in Patients With Severe Burn Injury

Morbidity and Mortality of Bloodstream Infections in Patients With Severe Burn Injury

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

Guidelines for the prevention of intravascular catheter-related infections

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