Evaluation of optical rhinometry for nasal provocation testing in allergic and nonallergic subjects

Luong, Amber U.; Cheung, Esther J.; Citardi, Martin J.; Batra, Pete S.

doi:10.1016/j.otohns.2010.03.030

Cited by 11 publications

(16 citation statements)

References 10 publications

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“…Optical rhinometry is a relatively new technique, used not only in nasal allergy diagnostics [14] but also as an objective assessment of the effectiveness of treatment and physiological changes in the nasal cavity. There is only one publication documenting the specificity and sensitivity of ORM versus ARM in the literature on the subject.…”

Section: Discussionmentioning

confidence: 99%

Specificity and sensitivity assessment of selected nasal provocation testing techniques

Krzych‐Fałta¹,

Furmańczyk²,

Samoliński³

2016

pdia

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IntroductionNasal provocation testing involves an allergen-specific local reaction of the nasal mucosa to the administered allergen.AimTo determine the most objective nasal occlusion assessment technique that could be used in nasal provocation testing.Material and methodsA total of 60 subjects, including 30 patients diagnosed with allergy to common environmental allergens and 30 healthy subjects were enrolled into the study. The method used in the study was a nasal provocation test with an allergen, with a standard dose of a control solution and an allergen (5,000 SBU/ml) administered using a calibrated atomizer into both nostrils at room temperature. Early-phase nasal mucosa response in the early phase of the allergic reaction was assessed via acoustic rhinometry, optical rhinometry, nitric oxide in nasal air, and tryptase levels in the nasal lavage fluid.ResultsIn estimating the homogeneity of the average values, the Levene’s test was used and receiver operating characteristic curves were plotted for all the methods used for assessing the nasal provocation test with an allergen. Statistically significant results were defined for p < 0.05. Of all the objective assessment techniques, the most sensitive and characteristic ones were the optical rhinometry techniques (specificity = 1, sensitivity = 1, AUC = 1, PPV = 1, NPV = 1).ConclusionsThe techniques used showed significant differences between the group of patients with allergic rhinitis and the control group. Of all the objective assessment techniques, those most sensitive and characteristic were the optical rhinometry.

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Section: Discussionmentioning

confidence: 99%

Specificity and sensitivity assessment of selected nasal provocation testing techniques

Krzych‐Fałta¹,

Furmańczyk²,

Samoliński³

2016

pdia

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“…Recent publications from our laboratory have reported that optical rhinometry correlates well with a patient's subjective symptoms in allergic rhinitis . This technique for nasal patency has several advantages to other techniques such as acoustic rhinometry and acoustic rhinomanometry including ability to obtain continuous measurements and minimal user variability, but further work is necessary to prove its utility in the clinical setting.…”

Section: Discussionmentioning

confidence: 99%

“…Optical rhinometry has shown positive correlation with symptom scores for nasal congestion in nasal provocation testing with histamine and other known antigens. Changes in optical density measured by optical rhinometry also correlate with changes in nasal cavity cross‐sectional area as measured by acoustic rhinometry …”

mentioning

confidence: 87%

Optical rhinometry in nonallergic irritant rhinitis: a capsaicin challenge study

Lambert

Fakhri

Citardi

et al. 2013

Int Forum Allergy Rhinol

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“…Some studies support the use of optical rhinometry in allergen provocation challenges. 84,85 Specifically, Luong et al reported that this method can assess changes in nasal patency during challenges with histamine. 85 Also, Krzych-Fałta et al performed optical rhinometry in 30 patients with allergic rhinitis and 30 healthy subjects.…”

Section: Optical Rhinometrymentioning

confidence: 99%

“…84,85 Specifically, Luong et al reported that this method can assess changes in nasal patency during challenges with histamine. 85 Also, Krzych-Fałta et al performed optical rhinometry in 30 patients with allergic rhinitis and 30 healthy subjects. They reported that the level of light extinction in patients with allergic rhinitis returned to baseline after 28.15 minutes.…”

Section: Optical Rhinometrymentioning

confidence: 99%

Objective Assessment of Nasal Patency

et al. 2017

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The aim to objectify nasal airflow and patency is ongoing—many methods have been suggested, often lacking clinical relevance or showing weak correlations with patients' symptoms. It is crucial to thoroughly consult our patients presenting with nasal obstruction—and to inform them about realistic possible surgical outcomes. Often, a perfect-looking internal nose with a straight septum and normal-appearing turbinates does not guarantee a happy, symptom-free “owner.” A review of the literature and the current technical market is presented here to facilitate the rhinosurgeon's decision to perform pre- and postoperative objective measurements of nasal airflow. Recommendations by the societies have been included.

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Evaluation of optical rhinometry for nasal provocation testing in allergic and nonallergic subjects

Cited by 11 publications

References 10 publications

Specificity and sensitivity assessment of selected nasal provocation testing techniques

Specificity and sensitivity assessment of selected nasal provocation testing techniques

Optical rhinometry in nonallergic irritant rhinitis: a capsaicin challenge study

Objective Assessment of Nasal Patency

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