Evaluation of Nutritional Status in Cancer Patients Receiving Radiotherapy

Ünsal, Diclehan; Menteş, B. Bülent; Akmansu, Müge; Üner, Aytuğ; Oğuz, Mehmet; Pak, Yücel

doi:10.1097/01.coc.0000198745.94757.ee

Cited by 145 publications

(89 citation statements)

References 27 publications

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“…Case series, uncontrolled studies, and articles based on expert opinion alone will receive a level of V. Rationale: There is clear evidence that nutrition screening with appropriate screening tools will identify cancer patients who are malnourished. [26][27][28][29][30][31][32] Among the developed screening tools are the patient generated subjective global assessment (PGSGA), 27,28 the subjective global assessment (SGA), 26,27,30,31 and the nutrition risk index (NRI). 30 They all have validated specificity and sensitivity in cancer patients, have been the subjects of prospective clinical trials, and share an emphasis on clinical data.…”

Section: Methodsmentioning

confidence: 99%

A.S.P.E.N. Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation

August

Huhmann

2009

J Parenter Enteral Nutr

421

279

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Section: Methodsmentioning

confidence: 99%

A.S.P.E.N. Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation

August

Huhmann

2009

J Parenter Enteral Nutr

421

279

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“…It is reported that, before the start of radiotherapy (rt) or chemoradiotherapy, 3% -52% of patients are malnourished 1,4 . During rt and chemoradiotherapy, the percentage of malnourished patients rises to 44% -88% 1,5 . Malnutrition in hnscc is not only affected by radiation, it can also be further exaggerated by mechanical difficulties (swallowing or chewing, for example) resulting from mass effect or prior surgery, by poor nutrition related to heavy smoking and excessive alcohol consumption, and by the toxicities of multimodal cancer treatment such as chemoradiotherapy 6 .…”

Section: Introductionmentioning

confidence: 99%

A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy

Kohli¹,

Corns

Vinnakota

et al. 2018

Current Oncology

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Malnutrition is a frequent manifestation in patients with head-and-neck cancer undergoing radiation therapy and a major contributor to morbidity and mortality. Thus, body composition is an important component of an overall evaluation of nutrition in cancer patients. Malnutrition is characterized by weight loss, loss of muscle mass, changes in cell membrane integrity, and alterations in fluid balance. Bioelectrical impedance analysis is a method to analyze body composition and includes parameters such as intracellular water content, extracellular water content, and cell membrane integrity in the form of a phase angle (Φ). Bioelectrical impedance analysis has consistently been shown to have prognostic value with respect to mortality and morbidity in patients undergoing chemotherapy. The goal of the present study was to evaluate the relationship between Φ, time, intracellular water content, and weight for head-and-neck cancer patients undergoing radiotherapy. The results demonstrate that Φ decreases with time and increases with intracellular water content and weight.

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“…Nearly 20% of patients may fail in completing planned radiation therapy. Malnutrition may in turn affect the safety and outcome of the surgery [42] . Anastomotic leakage may be among the related complications.…”

Section: What Will We Do To Alleviate Sur-gical Concerns Following Ramentioning

confidence: 99%

Neoadjuvant chemotherapy for locally advanced gastric cancer: With or without radiation

Wu¹

2012

WJGS

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The role of perioperative chemotherapy for gastric cancer has been established for gastric cancers in their advanced stage. In most parts of the world, even in Japan and Korea, local recurrence of gastric cancer following curative resection remains a problem. Should radiation be added to chemotherapy to achieve better local and regional control? What is the current evidence? What are the concerns regarding neoadjuvant chemoradiation in terms of safety, efficacy and survival benefit? After a serious review of the literature, the authors conclude that it is still too early to get a definitive answer but radiation seems promising. It may bring a higher pathological response rate. Rationally, more high level clinical trials are needed to confirm the role of radiotherapy in the neoadjuvant setting or to ascertain subsets of patients who may benefit from it. It is of note that surgeons should pay attention to possible complicated circumstances following radiotherapy, maintain proper nutrition status and minimize the occurrence of postoperative complications. As few data are available in Japan and Korea, interpretation and implementation of neoadjuvant radiation or chemoradiation should be done with caution.

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Evaluation of Nutritional Status in Cancer Patients Receiving Radiotherapy

Abstract: The results of the present study may be helpful in planning an appropriate nutritional support for cancer patients undergoing radiotherapy according to the irradiation site.

Cited by 145 publications

References 27 publications

A.S.P.E.N. Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation

A.S.P.E.N. Clinical Guidelines: Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation

A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy

Neoadjuvant chemotherapy for locally advanced gastric cancer: With or without radiation

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