Evaluation of noncompliance in schizophrenia patients using electronic monitoring (MEMS®) and its relationship to sociodemographic, clinical and psychopathological variables

Artiles, Francisco Javier Acosta; Bosch, Esperanza; Sarmiento, G.; Juanes, N.; Caballero-Hidalgo, Araceli; Mayans, Teresa

doi:10.1016/j.schres.2008.09.007

Cited by 106 publications

(119 citation statements)

References 34 publications

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“…patients or psychiatrists), and five of these studies [AscherSvanum 2006;Janssen et al 2006;Novick et al 2010;Olfson et al 2006;Valenstein et al 2004] included more than 500 subjects. Countries where studies were conducted included Spain [Acosta et al 2009;Novick et al 2010], the USA [Aldebot and de Mamani 2009;Hudson et al 2004;Olfson et al 2006;Valenstein et al 2004;Weiden et al 2004b], Switzerland [Borras et al 2007], Germany [Janssen et al 2006;Linden et al 2001;Loffler et al 2003], Australia [McCann et al 2009], Denmark [Novick et al 2010], Italy [Novick et al 2010], Portugal [Novick et al 2010], Ireland [Novick et al 2010], the UK [Novick et al 2010] and Austria [Rettenbacher et al 2004]. Eleven studies [Aldebot and de Mamani 2009;Borras et al 2007;Hudson et al 2004;Janssen et al 2006;Loffler et al 2003;McCann et al 2009;Novick et al 2010;Olfson et al 2006;Rettenbacher et al 2004;Weiden et al 2004b] used subjective measures of adherence such as interviews and questionnaires completed by clinicians or patients, and four studies [Acosta et al 2006;Linden et al 2001;Valenstein et al 2004] used objective measures of adherence such as the Medication Event Monitoring System (MEMS, AARDEX Group Ltd., Switzerland) ...…”

Section: Factors Influencing Adherence Ratesmentioning

confidence: 99%

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Higashi¹,

Medic

Littlewood

et al. 2013

Therapeutic Advances in Psychopharmacology

453

381

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Background: Nonadherence to medication is a recognized problem and may be the most challenging aspect of treatment. Methods:We performed a systematic review of factors that influence adherence and the consequences of nonadherence to the patient, healthcare system and society, in patients with schizophrenia. Particular attention was given to the effect of nonadherence on hospitalization rates, as a key driver of increased costs of care. A qualitative systematic literature review was conducted using a broad search strategy using disease and adherence terms. Due to the large number of abstracts identified, article selection was based on studies with larger sample sizes published after 2001. Thirty-seven full papers were included: 15 studies on drivers and 22 on consequences, of which 12 assessed the link between nonadherence and hospitalization. Results: Key drivers of nonadherence included lack of insight, medication beliefs and substance abuse. Key consequences of nonadherence included greater risk of relapse, hospitalization and suicide. Factors positively related to adherence were a good therapeutic relationship with physician and perception of benefits of medication. The most frequently reported driver and consequence were lack of insight and greater risk of hospitalization respectively. Conclusions: Improving adherence in schizophrenia may have a considerable positive impact on patients and society. This can be achieved by focusing on the identified multitude of factors driving nonadherence.

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Section: Factors Influencing Adherence Ratesmentioning

confidence: 99%

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Higashi¹,

Medic

Littlewood

et al. 2013

Therapeutic Advances in Psychopharmacology

453

381

View full text Add to dashboard Cite

show abstract

“…10 These subjective methods can be easily implemented in the clinical setting but have questionable accuracy and tend to underestimate nonadherence. 11,12 The currently available objective methods to assess patient adherence include pill counts, electronic devices that capture pill container openings such as Medication Event Monitoring System (MEMS) bottle caps, and pharmacy refill records. 13 Electronic bottle caps and smart pill boxes, often considered the gold standard for assessing adherence, 14 are limited to reporting the event of container opening.…”

mentioning

confidence: 99%

Developing a Digital Medicine System in Psychiatry

Profit

Rohatagi

Zhao

et al. 2016

J. Clin. Psychiatry

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“…Other studies. [36,33] reported the absence of association with type of disease. On the contrary, Mert et al (2015) found that non-adherence rate was significantly higher in patients with bipolar disorder when compared to other types.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Risk Factors of Non-Adherence in Psychiatric Patients in Taif, Saudi Arabia

Alalyani¹

2017

WJPR

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Objectives: To estimate the prevalence of non-adherence to medication among and to explore the different reasons for drug non adherence among patient in mental health hospital in Taif city. Subjects and methods:It is a Cross-sectional descriptive study. The study included 255 patients who were following in Mental HealthHospital clinic. The total number was 255 patients, 233 patients were included in the study and 22 were excluded from the study according to eligibility criteria. The tool of the study was a self-administered questionnaire, which consists of three Parts: Demographic data, psychiatric diagnosis and reasons of not take the treatment. Result:Incidence of non-adherence was high (84.1%). The factors that increased the likelihood of non-adherence were absence of job, familial support and health education about medication use in addition to occurrence of side effects. Conclusion: The frequency of non-adherence is relatively high among the patients with psychiatric disorders in Taif city. Prevention strategies should focus on enhancing socioeconomic status (education and employment) and effective health education of patients to enable them to deal with adverse drug effects.

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Evaluation of noncompliance in schizophrenia patients using electronic monitoring (MEMS®) and its relationship to sociodemographic, clinical and psychopathological variables

Cited by 106 publications

References 34 publications

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Developing a Digital Medicine System in Psychiatry

Prevalence and Risk Factors of Non-Adherence in Psychiatric Patients in Taif, Saudi Arabia

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