“…The absence of recommendations on subjective medical image and video quality assessment shows the existence of a very complex problem: no unique optimal solution exists for all scenarios, since medical image quality is very much influenced by the contextual and the human influential factors (IFs) [108]- [109]. Context IFs include applications (e.g., diagnosis, surgery, training), clinical factors (e.g., emergency care, lesion subtleness, clinical region of interest), requirements (e.g., real-time/offline, location), medical data (clinical information (anatomical, functional physiological), acquisition modalities (e.g., ultrasound, X-ray, MRI, EEG, ECG), data types (e.g., signal, images (monochrome, colour), video (monochrome, colour)); while human IFs include expertise (e.g., years of experience, major, cultural background, educational background, pedagogical implications [47], [55]), as well as emotional state (e.g., tiredness, stress, eyestrain [110]). When context and end-users differ, the purpose of the study may require a specific test protocol.…”