Evaluation of Nexus of Dental Erosion and Gastro-esophageal Reflux Disease: A Hospital-based Cross-sectional Study

Ramugade, Manoj Mahadeo; Sayed, Abrar; Sapkale, Kishor; Sonkurla, Sapna

doi:10.7860/jcdr/2019/42753.13385

Cited by 1 publication

(5 citation statements)

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“…The 86 remaining studies were analyzed in detail for compliance with the inclusion criteria, which led to the exclusion of 58 studies ( Figure 1 ). Finally, the remaining 28 original studies were considered eligible and included in the final meta-analysis ( Table 2 ) [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ].…”

Section: Resultsmentioning

confidence: 99%

“…The control population was represented in 21 studies [ 21 , 24 , 25 , 26 , 27 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 38 , 39 , 40 , 41 , 42 , 43 , 45 , 47 ]. In most studies, validated instrumental examination methods were used to diagnose GERD ( n = 17) [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 32 , 34 , 35 , 36 , 38 , 42 , 43 , 44 ], and dental examination was used to diagnose DE using validated Eccles and Jenkins criteria ( n = 7) [ 21 , 22 , 23 , 24 , 28 , 29 , 31 ], Smith and Knight ( n = 6) [ 26 , 27 , 30 , 32 , 39 ,…”

Section: Resultsmentioning

confidence: 99%

“…In the studies conducted to date, the frequency of DE in GERD patients varies widely from 3.226% to 95.604% [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ]. Through the pooling of the results of the 28 selected studies in the present meta-analysis, the pooled incidence of DE in GERD patients was determined as 51.524% (95 CI: 39.742–63.221).…”

Section: Discussionmentioning

confidence: 99%

“… Forest plot showing the cumulative risk (OR) of DE in GERD patients [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ]. …”

Section: Figurementioning

confidence: 99%

“…The control population was represented in 21 studies [21,[24][25][26][27][29][30][31][32][33][34][35][36][38][39][40][41][42][43]45,47]. In most studies, validated instrumental examination methods were used to diagnose GERD (n = 17) [21][22][23][24][25][26][27][28]30,32,[34][35][36]38,[42][43][44], and dental examination was used to diagnose DE using validated Eccles and Jenkins criteria (n = 7) [21][22][23][24]28,29,31], Smith and Knight (n = 6) [26,27,30,32,39,…”

Section: Description Of the Studiesmentioning

confidence: 99%

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Prevalence and Risk of Dental Erosion in Patients with Gastroesophageal Reflux Disease: A Meta-Analysis

et al. 2022

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Aim: The present paper aims to systematize data concerning the prevalence and risk of dental erosion (DE) in adult patients with gastroesophageal reflux disease (GERD) compared to controls. Materials and methods: Core electronic databases, i.e., MEDLINE/PubMed, EMBASE, Cochrane, Google Scholar, and the Russian Science Citation Index (RSCI), were searched for studies assessing the prevalence and risk of DE in adult GERD patients with publication dates ranging from 1 January 1985 to 20 January 2022. Publications with detailed descriptive statistics (the total sample size of patients with GERD, the total sample size of controls (if available), the number of patients with DE in the sample of GERD patients, the number of patients with DE in the controls (if available)) were selected for the final analysis. Results: The final analysis included 28 studies involving 4379 people (2309 GERD patients and 2070 control subjects). The pooled prevalence of DE was 51.524% (95 CI: 39.742–63.221) in GERD patients and 21.351% (95 CI: 9.234–36.807) in controls. An association was found between the presence of DE and GERD using the random-effects model (OR 5.000, 95% CI: 2.995–8.345; I2 = 79.78%) compared with controls. When analyzing studies that only used validated instrumental methods for diagnosing GERD, alongside validated DE criteria (studies that did not specify the methodologies used were excluded), a significant association between the presence of DE and GERD was revealed (OR 5.586, 95% CI: 2.311–13.503; I2 = 85.14%). Conclusion: The meta-analysis demonstrated that DE is quite often associated with GERD and is observed in about half of patients with this extremely common disease of the upper gastrointestinal tract.

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