Evaluation of nasal culturing procedures and immunization as applied to the control of Bordetella bronchiseptica rhinitis in swine

Farrington, Daniel O.

doi:10.31274/rtd-180814-4449

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…1972;Farrington 1974;Nakase et al 1976) double s. c. vaccination of piglets was effective in restricting the development of pathological changes due to B. bronchiseptica. Inoculation into the nasal submucosa and i. p. immunization, on the other hand, proved to be only a mildly stimulating means of restricting the growth of B. bronchiseptica and the development of pathological changes.…”

Section: Discussionmentioning

confidence: 99%

Passive and Active Protection Against the Development of Pathological Changes in Piglets Infected with Bordetella bronchiseptica

Šišák¹,

Góis²,

Kuksa³

1979

Acta Vet. Brno

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Active and passive immunization of piglets against Bordetella bronchiseptica restricted the development of gross changes in the nasal turbinates and lung after intranasal or contact infection. Gnotobiotic piglets were used to test the effect of specific hyperimmune serum against B. bronchiseptica in relation to the concentration of intranasally administered organisms: infection with 10' colony-forming units (CFU) of B. bronchiseptica/ml did not produce turbinate atrophy in any of 6 serum-treated piglets, but did soin6of7 controls; infection with 10' CFU/mlproduced turbinate atrophy in 2 and lung lesions in 1 of 5 serum-treated piglets as against turbinate atrophy and lung lesions in 4 and 2 animals, respectively, out of 4 controls; infection with 10 8 CFU/ml produced turbinate atrophy in 3 and lung lesions in 4 of 5 serum-treated piglets as against atrophy and lung lesions in 5 and 4 animals, respectively, out of 5 controls.

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Section: Discussionmentioning

confidence: 99%

Passive and Active Protection Against the Development of Pathological Changes in Piglets Infected with Bordetella bronchiseptica

Šišák¹,

Góis²,

Kuksa³

1979

Acta Vet. Brno

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“…Nasal swab specimens were obtained from each sow just before farrowing and from each newborn pig at 3 days of age to determine if test swine were susceptible. The techniques for nasal swab specimen collection and the isolation and identification of B. bronchiseptica have been previously described (3,7,11).…”

mentioning

confidence: 99%

Mouse potency assay for Bordetella bronchiseptica bacterins

Goodnow¹,

Lehr²,

Shade³

et al. 1977

J Clin Microbiol

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A potency assay for Bordetella bronchiseptica bacterins has been developed using mice. The immunogenicities of three bacterins, B, C, and D, were evaluated for ability to prevent death in mice as compared with a reference standard bacterin (RSB-A). Bacterins RSB-A, B, and C were evaluated for ability to prevent death in mice as compared with a reference standard bacterin (RSB-A). Bacterins RSB-A, B, and C were evaluated in swine for efficacy against nasal turbinate atrophy. Swine immunized with RSB-A demonstrated 25% gross nasal turbinate atrophy (GNTA), whereas nonimmunized swine had 85% GNTA. Swine vaccinated with bacterins B and C demonstrated 0 and 100% GNTA, respectively, whereas the nonimmunized groups had 64 and 75% GNTA, respectively. RSB-A and bacterins B, C, and D provided average mouse survivals of 94, 88, 49, and 32%, respectively when the mice were given 1/10,000 of a recommended swine-immunizing dose, whereas an average of 88% of the unvaccinated mice died.

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Evaluation of nasal culturing procedures and immunization as applied to the control of Bordetella bronchiseptica rhinitis in swine

Cited by 2 publications

References 15 publications

Passive and Active Protection Against the Development of Pathological Changes in Piglets Infected with Bordetella bronchiseptica

Passive and Active Protection Against the Development of Pathological Changes in Piglets Infected with Bordetella bronchiseptica

Mouse potency assay for Bordetella bronchiseptica bacterins

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