Evaluation of Nanoparticles Covalently Bound with BODIPY for Their Photodynamic Therapy Applicability
Miryam Chiara Malacarne,
Enrico Caruso,
Marzia Bruna Gariboldi
et al.
Abstract:Photodynamic therapy (PDT) relies on the combined action of a photosensitizer (PS), light at an appropriate wavelength, and oxygen, to produce reactive oxygen species (ROS) that lead to cell death. However, this therapeutic modality presents some limitations, such as the poor water solubility of PSs and their limited selectivity. To overcome these problems, research has exploited nanoparticles (NPs). This project aimed to synthesize a PS, belonging to the BODIPY family, covalently link it to two NPs that diffe… Show more
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