Evaluation of nanoparticles as promising alternative antimicrobials

Abstract

The search for new substances capable of inhibiting the growth of microorganisms is relevant. Therefore, an assessment was made of the effect of carbon nanoparticles on the growth and biofilm formation of microbial isolates from the surfaces of anthropogenic environmental objects. It has been established that carbon nanoparticles on the C60 + PVP + AC960 diamond platform are able to suppress the growth, reproduction and ability to biofilm formation of gram-positive and gram-negative prokaryotes, as well as fungi of the genus Candida and Aspergillus. Under the influence of C60+AC960 fullerenes, the biofilm-generation ability of Staphylococcus epidermidis, Bacillus cereus, Escherichia coli, and Candida albicans was significantly inhibited. These data provide a basis for further study of these compounds as a promising antimicrobial agent. Keywords: Antimicrobial action, carbon nanoparticles, biofilm formation, fullerenes, nanodiamonds.