Evaluation of myocardial work in patients with resistant arterial hypertension

Hygídio, Daniel de Andrade; Bihan, David Le; Souza, Jonathan Batista; Barretto, Rodrigo Bellio de Mattos; Mathias, Wilson; Sousa, Márcio Gonçalves de

doi:10.1111/echo.15467

Cited by 2 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, de Andrade Hygidio et al 31 . showed lower GWE and higher GWW in patients with resistant arterial hypertension (AH), in comparison to subjects with controlled AH and without AH.…”

Section: Mw Analysis As a New Echocardiographic Technique For LV Glob...mentioning

confidence: 99%

“…showed lower GWE and higher GWW in patients with resistant arterial hypertension (AH), in comparison to subjects with controlled AH and without AH. Particularly, that transversal single‐center study exclude patients with atrial fibrillation and left bundle branch block, aiming at avoiding further confusion factors altering MW analysis 31 . On the other hand, those exclusion factors may dissociate that population from the real‐world spectrum of patients 31 …”

Section: Mw Analysis As a New Echocardiographic Technique For LV Glob...mentioning

confidence: 99%

“…Particularly, that transversal single-center study exclude patients with atrial fibrillation and left bundle branch block, aiming at avoiding further confusion factors altering MW analysis. 31 On the other hand, those exclusion factors may dissociate that population from the real-world spectrum of patients. 31 The brachial cuff-measured arterial systolic pressure makes MW evaluation easily achievable.…”

Section: Mw Clinical Applications and Expected Limitations In Routine...mentioning

confidence: 99%

“…2,30 To note, Manganaro et al 30 reported a number of important limitations as well, including two thirds of patients not analyzable by the available software (only one brand available on the global market), and the lack of data aimed to know whether the study results might be extrapolated to non-Caucasian European subjects. However, de Andrade Hygidio et al 31 showed lower GWE and higher GWW in patients with resistant arterial hypertension (AH), in comparison to subjects with controlled AH and without AH. Particularly, that transversal single-center study exclude patients with atrial fibrillation and left bundle branch block, aiming at avoiding further confusion factors altering MW analysis.…”

Section: Mw Clinical Applications and Expected Limitations In Routine...mentioning

confidence: 99%

“…31 On the other hand, those exclusion factors may dissociate that population from the real-world spectrum of patients. 31 The brachial cuff-measured arterial systolic pressure makes MW evaluation easily achievable. 2 However, pressure curve estimation accuracy tends to vary along the cardiac cycle, more and more in the presence of different hemodynamic conditions, and peripheral arterial disease.…”

Section: Mw Clinical Applications and Expected Limitations In Routine...mentioning

confidence: 99%

See 4 more Smart Citations

From ejection fraction, to myocardial strain, and myocardial work in echocardiography: Clinical impact and controversies

Dell'Angela,

Nicolosi

2024

Echocardiography

View full text Add to dashboard Cite

Enhancing an echocardiographic tool, aimed to detect even subtle left ventricular (LV) systolic function abnormalities, capable of obtaining both early diagnosis and risk prediction of heart disease, represents an ambitious, attractive, and arduous purpose in the modern era of cardiovascular imaging. Ideally, that tool should be simple, reliable, and reproducible, in order to be concretely applied in routine clinical practice. Importantly, that technique should be physiologically plausible and useful both at the population‐level, as well as in the individual subject. For a long time, LV ejection fraction (EF) has been considered the first‐line parameter for assessing LV global systolic function, strictly related to the prognosis, at least in some settings. However, LV EF limitations are well‐known, even though frequently overemphasized, including its load‐dependency. Therefore, myocardial strain techniques have been proposed, deemed able to disclose even subtle early LV function anomalies. Nevertheless, many disadvantages of myocardial strain have been reported as well. More recently, myocardial work (MW) analysis has been introduced as a new echocardiographic tool for the evaluation of LV global systolic function, attempting to overcome EF and strain disadvantages. However, MW has shown many limits as well. Notwithstanding, LV EF still remains a landmark functional classification marker for heart failure and cardiac oncology, allowing reliable fast reassessment of LV function changes during patient management, in order to guide treatment in individual cases as well. Notably, global longitudinal strain and MW parameters seem to show better meaningful results at the population‐level, but controversial clinical impact, major limitations, wide cut‐offs spread and overlap, when the single value needs to be applied to the single case. Taking into account the recent literature‐based evidence, the scope of the present narrative critical review is trying to delineate the different types of information given by the described LV global systolic function parameters, both at the population‐level and in the individual case, in order to trace a comparative analysis of advantages and limitations in clinical practice.

show abstract

“…However, de Andrade Hygidio et al 31 . showed lower GWE and higher GWW in patients with resistant arterial hypertension (AH), in comparison to subjects with controlled AH and without AH.…”

Section: Mw Analysis As a New Echocardiographic Technique For LV Glob...mentioning

confidence: 99%

Section: Mw Analysis As a New Echocardiographic Technique For LV Glob...mentioning

confidence: 99%

Section: Mw Clinical Applications and Expected Limitations In Routine...mentioning

confidence: 99%

Section: Mw Clinical Applications and Expected Limitations In Routine...mentioning

confidence: 99%

Section: Mw Clinical Applications and Expected Limitations In Routine...mentioning

confidence: 99%

See 3 more Smart Citations

From ejection fraction, to myocardial strain, and myocardial work in echocardiography: Clinical impact and controversies

Dell'Angela,

Nicolosi

2024

Echocardiography

View full text Add to dashboard Cite

show abstract

Interrelationships between Peak Strain Dispersion, Myocardial Work Indices, Isovolumetric Relaxation and Systolic–Diastolic Coupling in Middle-Aged Healthy Subjects

Minczykowski,

Guzik,

Sajkowska

et al. 2023

JCM

View full text Add to dashboard Cite

In echocardiography, peak strain dispersion (PSD) is the standard deviation of the time to peak longitudinal strain for each left ventricular (LV) segment during systole. It assesses the coordination and synchrony of LV segment contractility. Global work efficiency (GWE) and global wasted work (GWW) quantify LV myocardial work and, if impaired, the coupling between LV systolic contraction and early relaxation. Isovolumetric relaxation (IVRT) measures the duration of initial LV relaxation, while the ratio of early diastolic recoil to systolic excursion (E′VTI/S′VTI) describes systolic–diastolic coupling. We evaluated these parameters in 69 healthy subjects and found that PSD correlated negatively with GWE (r = −0.49, p < 0.0001) and E′VTI/S′VTI (r = −0.44, p = 0.0002), but positively with GWW (r = 0.4, p = 0.0007) and IVRT (r = 0.53, p < 0.0001). GWE correlated negatively with GWW (r = −0.94, p < 0.0001) and IVRT (r = −0.30, p = 0.0127), but positively with E′VTI/S′VTI (r = 0.3, p = 0.0132). In addition, E′VTI/S′VTI was negatively correlated with GWW (r = −0.35, p = 0.0032) and IVRT (r = −0.36, p = 0.0024). These associations remained significant after adjustment for sex, age and LV mass index of the subjects. In conclusion, there is an interaction between measures of LV asynchrony, myocardial work, diastolic function and its systolic–diastolic coupling in middle-aged healthy subjects. The clinical value of these interactions requires further investigation.

show abstract

Evaluation of myocardial work in patients with resistant arterial hypertension

Cited by 2 publications

References 17 publications

From ejection fraction, to myocardial strain, and myocardial work in echocardiography: Clinical impact and controversies

From ejection fraction, to myocardial strain, and myocardial work in echocardiography: Clinical impact and controversies

Interrelationships between Peak Strain Dispersion, Myocardial Work Indices, Isovolumetric Relaxation and Systolic–Diastolic Coupling in Middle-Aged Healthy Subjects

Contact Info

Product

Resources

About