Evaluation of metacarpophalangeal joint synovitis in rheumatoid arthritis by power Doppler technique: relationship between synovial vascularization and periarticular bone mineral density

Özgöçmen, Salih; Kiris, Adem; Kocakoç, Ercan; Ardıçoğlu, Özge; Kamanlı, Ayhan

doi:10.1016/j.jbspin.2003.06.003

Cited by 22 publications

(11 citation statements)

References 25 publications

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“…24 As discussed in previous reports on resting musculoskeletal tissue, the RI is usually expected to be high with low diastolic flow. 7,8,25,26 Our results showed a significant negative correlation between mean RI and CFS, indicating that these 2 methods are in good agreement. On the other hand, we did not observe a statistically significant correlation between mean RI or CFS with patients' ESR or CRP levels in accordance with previous reports.…”

Section: Patient With Active Diseasesupporting

confidence: 56%

“…8 Terslev and colleagues showed increased RIs in parallel to the improvement in disease activity with etanercept treatment. 24 As discussed in previous reports on resting musculoskeletal tissue, the RI is usually expected to be high with low diastolic flow.…”

Section: Patient With Active Diseasementioning

confidence: 97%

“…On the other hand, we did not observe a statistically significant correlation between mean RI or CFS with patients' ESR or CRP levels in accordance with previous reports. 8,18,19 RI may be influenced by alterations in vascular compliance in inflamed synovium. 8 Furthermore, sensitivity of equipment, excessive pressure application to the joint during examination, or intra-articular increased pressure caused by prolonged inflammatory processes are factors that potentially affect RIs.…”

Section: Patient With Active Diseasementioning

confidence: 99%

“…In addition to mapping the vascularization of the joints of RA patients with PDUS, flow patterns in the inflamed joints can be evaluated using spectral Doppler analysis. 7,8 The aim of this prospective cross-sectional study was to assess vascularization of the synovium and flow pattern in hand joints [metacarpophalangeal (MCP) joints and ulnar stiloid (USTL)] of RA patients using PDUS and spectral Doppler analysis and to determine the accuracy of PDUS in detecting overall disease activity in RA patients.…”

mentioning

confidence: 99%

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Power Doppler assessment of overall disease activity in patients with rheumatoid arthritis

Kiris

Özgöçmen

Kocakoç

et al. 2005

J of Clinical Ultrasound

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Section: Patient With Active Diseasesupporting

confidence: 56%

Section: Patient With Active Diseasementioning

confidence: 97%

Section: Patient With Active Diseasementioning

confidence: 99%

mentioning

confidence: 99%

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Power Doppler assessment of overall disease activity in patients with rheumatoid arthritis

Kiris

Özgöçmen

Kocakoç

et al. 2005

J of Clinical Ultrasound

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“…2). Joint destruction is closely associated with increased vascularization and flow pattern (13,14). Demonstration of this vascularization during the early period of the disease can lead to an early diagnosis of RA and may lead to effective treatment before erosions and bony destruction occur.…”

Section: Rheumatoid Arthritismentioning

confidence: 99%

Doppler US in rheumatic diseases with special emphasis on rheumatoid arthritis and spondyloarthritis

Toprak

Kılıç

Serter³

et al. 2013

Diagn Interv Radiol

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Developments in digital ultrasonography (US) technology and the use of high-frequency broadband transducers have increased the quality of US imaging, particularly of superficial tissues. Thus, US, particularly color US or power Doppler US, in which high-resolution transducers are used, has become an important imaging modality in the assessment of rheumatic diseases. Furthermore, therapeutic interventions and biopsies can be performed under US guidance during the assessment of lesions. In this era of effective treatments, such as biologics, improvements in synovial inflammation in rheumatoid arthritis as well as changes in enthesitis in spondyloarthropathies, including ankylosing spondylitis and psoriatic arthritis, can be monitored effectively using gray-scale and/ or power Doppler US. US is also a good imaging modality for crystal arthropathies, including gout and pseudogout, in which synovitis, erosions, tophi, and crystal deposition within or around the joint can be visualized readily. Vascular and tenosynovial structures, as well as the salivary glands, can be assessed with US in vasculitis and connective tissue disorders, including systemic lupus erythematosus and Sjögren's syndrome. Current research is focused on improving the sensitivity, specificity, validity, and reproducibility of US findings. In this review, we summarized the role of US, particularly power Doppler US, in rheumatic diseases and inflammation in superficial tissues.

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Clinical and Ultrasound‐Based Composite Disease Activity Indices in Rheumatoid Arthritis: Results From a Multicenter, Randomized Study

Mandl

Bálint

Brault

et al. 2013

Arthritis Care & Research

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Objective. To evaluate the metrologic properties of composite disease activity indices in rheumatoid arthritis (RA), utilizing information derived from clinical, gray-scale (GS), and power Doppler (PD) ultrasound examinations, and to assess the classification of patients according to disease activity using such indices. Methods. This ancillary study utilized data from a multicenter, prospective, randomized, parallel-group study conducted in subjects with moderate RA randomized to receive etanercept and methotrexate (ETN ؉ MTX) or usual care (various disease-modifying antirheumatic drugs [DMARDs]). In multimodal indices, the 28 swollen joint count was either supplemented or replaced by clinically nonswollen joints in which the presence of synovitis was detected either by GS and/or PD and was calculated according to the Disease Activity Score in 28 joints (DAS28) or the Simplified Disease Activity Index (SDAI). Reliability, external validity, and discriminative capacity were calculated at baseline/screening by intraclass correlation coefficient, Pearson's correlation, and standardized response mean, respectively. Results. Data from 62 patients (mean

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Evaluation of metacarpophalangeal joint synovitis in rheumatoid arthritis by power Doppler technique: relationship between synovial vascularization and periarticular bone mineral density

Cited by 22 publications

References 25 publications

Power Doppler assessment of overall disease activity in patients with rheumatoid arthritis

Power Doppler assessment of overall disease activity in patients with rheumatoid arthritis

Doppler US in rheumatic diseases with special emphasis on rheumatoid arthritis and spondyloarthritis

Clinical and Ultrasound‐Based Composite Disease Activity Indices in Rheumatoid Arthritis: Results From a Multicenter, Randomized Study

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