Evaluation of mean shift, ComBat, and CycleGAN for harmonizing brain connectivity matrices across sites
Hanliang Xu,
Nancy R. Newlin,
Michael E. Kim
et al.
Abstract:Connectivity matrices derived from diffusion MRI (dMRI) provide an interpretable and generalizable way of understanding the human brain connectome. However, dMRI suffers from inter-site and between-scanner variation, which impedes analysis across datasets to improve robustness and reproducibility of results. To evaluate different harmonization approaches on connectivity matrices, we compared graph measures derived from these matrices before and after applying three harmonization techniques: mean shift, ComBat,… Show more
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