Evaluation of maximum voided volume in Korean children by use of a 48‐h frequency volume chart

Abstract

Study Type – Diagnostic (validating cohort) Level of Evidence 2a What's known on the subject? and What does the study add? The relationship between the maximum voided volume followed a linear curve. The formula presented, bladder capacity (mL) = 12 ×[age (years) + 11], is thought to be a reasonable one for Korean children. Korean children have a smaller bladder capacity than that reported in previous Western studies. OBJECTIVE To develop practical guidelines for the prediction of normal bladder capacity in Korean children measured by a frequency volume chart (FVC), maximum voided volume (MVV) is an important factor in the diagnosis of children with abnormal voiding function. SUBJECTS AND METHODS In all, 298 children, aged 3–13 years, with no history of voiding disorders volunteered for the study. The MVV was determined in 219 subjects by use of a completely recorded FVC. RESULTS Linear regression analysis was used to define the exact relationship between age and bladder capacity. An approximate formula related age to bladder capacity as follows: bladder capacity (mL) = 12 ×[age (years) + 11]. CONCLUSIONS The relationship between the MVV measured by a FVC by age (3–13 years) of Korean children followed a linear curve. When applied to normal voiding patterns, the formula presented appears to be a reasonable one for Korean children.

Can recording only the day-time voided volumes predict bladder capacity?

“…When using eMVVmax to determine the bladder capacity in normal children, decreased bladder capacity was diagnosed as little as by using the real MVV. In addition, the formula for eMVVmax by age is in close agreement with the formula for the MVV by age in our previous study [ 10 ], and therefore it is considered that eMVVmax (=MVVDT×1.25) can sufficiently replace the MVV if necessary. It should be noted that the formula of Pearson's correlation (eMVVmax=11.8×age (years)+158.2) suggests that applying MVVDT×1.25 seems likely to overestimate bladder capacity for children under 5 years of age.…”

“…Linear regression analysis suggested the following formula for estimation of eMVVmax and eMVVmin by age: eMVVmax (mL)=11.8×age (years)+158.2 ( r 2 =0.244, p<0.001), eMVVmin (mL)=4.6×age (years)+200.1 ( r 2 =0.117, p<0.001). The formula derived using the eMVVmax was similar to a previously reported formula for bladder capacity [ 10 ].…”

Efficacy and Tolerability of Anticholinergics in Korean Children with Overactive Bladder: A Multicenter Retrospective Study

“…The Korean Children's Continence and Enuresis Society reported maximum bladder capacity of healthy 219 children, aged 3 to 13 yr without history of voiding disorder was 232.7±84.6 mL (range, 161-301 mL) ( 16 ). In the current study, the maximum bladder capacity was significantly increased from 145.5±66.9 to 196.8±80.3 mL.…”

Efficacy and Tolerability of Solifenacin 5 mg Fixed Dose in Korean Children with Newly Diagnosed Idiopathic Overactive Bladder: a Multicenter Prospective Study

“…MBC was also increased from 180.5 ± 73.4 to 206.7 ± 79.7 mL after 12 weeks of treatment, although without statistical significance ( P = 0.247). The MBC of 219 healthy Korean children aged 3–13 years in a previous study was 232.7 ± 84.6 mL (range: 161–301 mL) from 3-day voiding diaries (17). Although the symptoms improved in the OAB patients in our current study, the MBC after a 12-week treatment with solifenacin was still less than that of the healthy population.…”