Evaluation of Matrix-Assisted Laser Desorption/Ionization Mass spectrometry for second-Generation Lignin Analysis

Richel, Aurore; Vanderghem, Caroline; Simon, Mathilde; Wathelet, Bernard; Paquot, Michel

doi:10.4137/aci.s10799

Cited by 47 publications

(54 citation statements)

References 22 publications

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“…Matrix-assisted laser desorption/ionization (MALDI) ToF mass spectrometry has provided another useful tool for herbaceous lignin analysis [73]. Aromatic acids α-cyano-4-hydroxycinnamic acid (CHCA) or 2,5-dihydroxybenzoic acid (2,5-DHB) were found to provide the best MALDI matrices.…”

Section: Mass Spectrometrymentioning

confidence: 99%

“…Mass spectrometry, in its numerous configurations, has been employed to characterize the structure of lignin [62,[67][68][69][70][71][72][73][74][75][76][77]. Time-offlight (ToF) secondary ion mass spectrometry (SIMS) is one such MS design that provides enhanced sensitivity to surface measurements of solid analytes with high mass spectral and spatial resolution, requires limited sample preparation, and yields rapid analyses over wide mass ranges [69][70][71][72]74,76].…”

Section: Mass Spectrometrymentioning

confidence: 99%

“…Ultimately, reproducible, in situ measurements of lignin structure have been coveted for decades. Lignin structure Functionality specific reactions [40][41][42][43][44][47][48][49][50] CZE [52] APPI-MS [67] CRS Microscopy [116,117] AFM [178] GC [44] DFT [88,180] GCMS [171] DE-MS [62] Dispersive Raman [92][93][94][95][96] DSC [60] ClO 2 [45] GLC-FID [54] ESI/MS [77] Potentiometry [44] Modified oximation [46] GLC-MS [54] MALDI-MSI [68] Ellipsometry [179] Headspace GC [55] SEM [71,75] MALDI/TOF [73] Fluorescence [102,103,120,131,176,177] TEM [103] RP-HPLC [53] MBMS [75] FTIR [13,44,…”

Section: Wet Chemistrymentioning

confidence: 99%

“…Periodate oxidation/GC [185] GC [189] MALDI/TOF [73] NMR [54,59,61,132,135,137,[157][158][159][160][161][165][166][167]172,[182][183][184]186,190,[192][193][194][195]319] GCMS [65,191] Permanganate oxidation [60] GLC-FID [54] pyGCMS [182,183,190] GLC-MS [54] LC [187,188] Ozonation [161] SEC [182,[184][185][186] pyTMAH [59,65] Thioacidolysis [182][183][184][185] Lignin molecular weight Acetobromination [221] GPC …”

Section: Wet Chemistrymentioning

confidence: 99%

See 3 more Smart Citations

Recent innovations in analytical methods for the qualitative and quantitative assessment of lignin

Lupoi

Singh

Parthasarathi

et al. 2015

Renewable and Sustainable Energy Reviews

292

188

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a b s t r a c tAs the attraction of creating biofuels and bio-based chemicals from lignocellulosic biomass has increased, researchers have been challenged with developing a better understanding of lignin structure, quantity and potential uses. Lignin has frequently been considered a waste-product from the deconstruction of plant cell walls, in attempts to isolate polysaccharides that can be hydrolyzed and fermented into fuel or other valuable commodities. In order to develop useful applications for lignin, accurate analytical instrumentation and methodologies are required to qualitatively and quantitatively assess, for example, what the structure of lignin looks like or how much lignin comprises a specific feedstock's cellular composition. During the past decade, various diverse strategies have been employed to elucidate the structure and composition of lignin. These techniques include using two-dimensional nuclear magnetic resonance to resolve overlapping spectral data, measuring biomass with vibrational spectroscopy to enable modeling of lignin content or monomeric ratios, methods to probe and quantify the linkages between lignin and polysaccharides, or refinements of established methods to provide higher throughput analyses, less use of consumables, etc. This review seeks to provide a comprehensive overview of many of the advancements achieved in evaluating key lignin attributes. Emphasis is placed on research endeavored in the last decade.

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Section: Mass Spectrometrymentioning

confidence: 99%

Section: Mass Spectrometrymentioning

confidence: 99%

Section: Wet Chemistrymentioning

confidence: 99%

Section: Wet Chemistrymentioning

confidence: 99%

See 2 more Smart Citations

Recent innovations in analytical methods for the qualitative and quantitative assessment of lignin

Lupoi

Singh

Parthasarathi

et al. 2015

Renewable and Sustainable Energy Reviews

292

188

View full text Add to dashboard Cite

show abstract

“…In some cases, MALDI was successfully applied to isolated narrow lignin fractions14, 15 but it has not yet evolved into a generally applicable routine method for different types of lignin 16, 17. ESI‐MS also has some inherent problems to grasp lignin as a whole: the analyte cannot be ionized uniformly owing to its rather heterogeneous chemical nature so that usually only smaller fragments are detected, and larger molecules are suppressed.…”

Section: Introductionmentioning

confidence: 99%

Getting Closer to Absolute Molar Masses of Technical Lignins

et al. 2018

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Determination of molecular weight parameters of native and, in particular, technical lignins are based on size exclusion chromatography (SEC) approaches. However, no matter which approach is used, either conventional SEC with a refractive index detector and calibration with standards or multi‐angle light scattering (MALS) detection at 488 nm, 633 nm, 658 nm, or 690 nm, all variants can be severely erroneous. The lack of calibration standards with high structural similarity to lignin impairs the quality of the molar masses determined by conventional SEC, and the typical fluorescence of (technical) lignins renders the corresponding MALS data rather questionable. Application of MALS detection at 785 nm by using an infrared laser largely overcomes those problems and allows for a reliable and reproducible determination of the molar mass distributions of all types of lignins, which has been demonstrated in this study for various and structurally different analytes, such as kraft lignins, milled‐wood lignin, lignosulfonates, and biorefinery lignins. The topics of calibration, lignin fluorescence, and lignin UV absorption in connection with MALS detection are critically discussed in detail, and a reliable protocol is presented. Correction factors based on MALS measurements have been determined for commercially available calibration standards, such as pullulan and polystyrene sulfonate, so that now more reliable mass data can be obtained also if no MALS system is available and these conventional calibration standards have to be resorted to.

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Importance of Surface Functionalities for Antibacterial Properties of Carbon Spheres

Adolfsson

Gołda-Cępa

Erdal

et al. 2019

Advanced Sustainable Systems

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Carbon spheres (CS) are interesting materials for antibacterial applications. Herein, CS are produced by a green process utilizing microwave‐assisted hydrothermal treatment of cellulose. The CS are then postmodified in acidic and basic solutions to evaluate the influence of different functionalities on antibacterial properties. CS contain OH/COOH, CC, and CO functionalities, while O‐CS produced by acid treatment of CS have additional COOH, and NH/NH2 groups, resulting in carbon spheres with negatively and positively charged groups in dispersion. Treatment with base (Na‐CS) removes low molecular weight species with oxygen and results in carbon spheres with the highest C/O ratio. CS, O‐CS, and Na‐CS have nonporous morphology and are in micro/nanometer sizes, although, smaller sized spheres, hollow spheres, and fragments are also attained in the case of O‐CS. O‐CS show antibacterial activity toward both Gram‐positive Staphylococcus aureus (S. aureus) and Gram‐negative Pseudomonas aeruginosa (P. aeruginosa). The minimum inhibitory concentration is 200 and 400 µg mL−1 for S. aureus and P. aeruginosa, respectively, and is achieved only after 3 h of incubation. Neither CS nor Na‐CS exhibit antibacterial activity. The antibacterial activity is suggested to originate from electrostatic interactions between O‐CS and the bacteria.

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Evaluation of Matrix-Assisted Laser Desorption/Ionization Mass spectrometry for second-Generation Lignin Analysis

Cited by 47 publications

References 22 publications

Recent innovations in analytical methods for the qualitative and quantitative assessment of lignin

Recent innovations in analytical methods for the qualitative and quantitative assessment of lignin

Getting Closer to Absolute Molar Masses of Technical Lignins

Importance of Surface Functionalities for Antibacterial Properties of Carbon Spheres

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