Evaluation of Mask-Induced Cardiopulmonary Stress

Bao, Riqiang; Ning, Guang; Sun, Yingxian; Pan, S.C.; Wang, Weiqing

doi:10.1001/jamanetworkopen.2023.17023

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…In healthy individuals, N95 masks cause minimal changes in blood gas and other physiological parameters during physical activity, even during very intense exercise [20]. A recent study of healthy volunteers suggested that even with mild exercise, prolonged wear of N95 masks can increase respiratory resistance, leading to a decrease in RR and SpO 2 within 1 hour and an increase in heart rate after 2 hours until the mask is removed [21]. Consistent with our research ndings, this study also did not nd any changes in BP, as healthy individuals can compensate for this cardiovascular overload.…”

Section: Discussionmentioning

confidence: 99%

Physiological Impact of N95 Masks on Obese Operating Room Staff: A Randomized Crossover Trial

犬牙,

钡,

高

et al. 2024

Preprint

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Background Obesity and mask both may increase the cardiopulmonary burden on medical staff. The physiological impact of surgical masks (SMs) and N95 masks on obese operating room staff remains uncertain. This study aimed to determine whether wearing N95 masks for 4 hours significantly affected physiological indices in obese medical staff compared to surgical masks (SMs). Methods In this randomized controlled two-phase crossover trial, the physiological impacts of wearing SMs and N95 masks for 4 hours was analysed among 20 obese operating room staff. The primary outcome was the change in venous carbon dioxide partial pressure (PvCO2) levels at 4-hour intervention. Secondary outcomes included venous oxygen pressure (PvO2), bicarbonate (HCO3−) and pH levels at 4-hour intervention, end-tidal carbon dioxide partial pressure (PetCO2), peripheral oxygen saturation (SpO2), respiratory rate (RR), pulse rate (PR) and blood pressure (BP) at immediately, 1 h, 2 h, 3 h, and 4 h after mask wear. Dyspnoea, palpitations, headache were assessed with the visual analogue scale (VAS) score. Linear mixed models were used for comparative analysis. Results Twenty participants (age 32.2 [6.0] years; BMI 32.8 [2.1] kg/m2; 45% female) completed the study. Compared with the no-mask condition, both SM and N95 masks wearing for 4 hours caused PvCO2, HCO3−, PetCO2, and RR levels increased slightly in obese operating room staff. N95 masks had a statistically significant rather than clinically significant impact on PvCO2 (mean [95% CI], 1.4 [0.8, 1.9], P < 0.001) and RR (0.6 [0.1, 1.1)], P = 0.023) compared with SM. There was no significant difference between the two types of masks in terms of PvO2, pH, SpO2, PR, and BP. The three subjective VAS scores gradually increased over wear time. After more than 2 hours, the N95 group showed significantly increased than SM group. Conclusion Obese operating room staff continuously wearing SM or N95 masks 4 hours showed almost no difference in physiological impacts. It is recommended to wear N95 masks under high-risk conditions for better protection. Clinical trial registration: NCT05950256.

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Section: Discussionmentioning

confidence: 99%

Physiological Impact of N95 Masks on Obese Operating Room Staff: A Randomized Crossover Trial

犬牙,

钡,

高

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…3,4 Wearing a mask may evoke many types of discomfort and lead to acute or chronic effects such as chest tightness, shortness of breath, anxiety, and palpitation. Bao et al 5 asked healthy individuals to continuously wear an N95 mask and observed the effects, which included a significantly increased heart rate after 1 hour of mask-wearing, significantly increased blood pressure (BP) after light exercise, and significantly increased plasma levels of norepinephrine and methoxyadrenaline after 14 hours of mask-wearing. It remains unclear whether wearing a mask for a long period can adversely affect BP in patients with hypertension and plasma glucose in those with diabetes, or whether mask-wearing makes it more challenging for these patients to control their BP and plasma glucose.…”

Section: Introductionmentioning

confidence: 99%

Effects of prolonged face mask use among patients with hypertension or diabetes during the COVID-19 pandemic

He,

Liu,

Zou

et al. 2024

J Int Med Res

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Objective We aimed to investigate the impacts of prolonged mask use on patients with hypertension or diabetes during the COVID-19 pandemic. Methods This study included patients with hypertension or diabetes who visited the outpatient department of Nanjing Yimin Hospital between 1 February 2022 and 31 January 2023. We compared the change in blood pressure (BP) and fasting plasma glucose in patients with hypertension or diabetes and adjustments to treatment between the group with prolonged mask-wearing group (≥20 hours/week) and the control group (<20 hours/week). Results Compared with the control group of hypertensive patients, the prolonged mask-wearing group had significantly higher diastolic blood pressure (DBP) and mean arterial pressure (MAP). These two groups had had similar DBP and MAP 1 year earlier. Likewise, the prolonged mask-wearing group of patients with diabetes had a greater need than the control group for upgraded treatment to reach their therapeutic goals. Conclusions This study suggests that prolonged mask use by patients with hypertension or diabetes has negative effects on hypertension and plasma glucose control. BP and plasma glucose monitoring should be improved in these patient populations and their treatment should be adjusted in a timely manner.

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Physiological Effects and Tolerance of Wearing Surgical and N95 Masks during Sleep in Normal Individuals and Patients with Mild-Moderate Obstructive Sleep Apnea: A Randomized Crossover Trial

Zhang,

Liu,

Zha

et al. 2024

The American Journal of Medicine

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Evaluation of Mask-Induced Cardiopulmonary Stress

Abstract: This randomized crossover trial evaluates the cardiopulmonary effects of extended use of the N95 mask during daily life.

Cited by 4 publications

References 6 publications

Physiological Impact of N95 Masks on Obese Operating Room Staff: A Randomized Crossover Trial

Physiological Impact of N95 Masks on Obese Operating Room Staff: A Randomized Crossover Trial

Effects of prolonged face mask use among patients with hypertension or diabetes during the COVID-19 pandemic

Physiological Effects and Tolerance of Wearing Surgical and N95 Masks during Sleep in Normal Individuals and Patients with Mild-Moderate Obstructive Sleep Apnea: A Randomized Crossover Trial

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