Abstract:Background: Lung ultrasound (LUS) can be an important imaging tool for the diagnosis and assessment of lung involvement. Ultrasound sonograms have been confirmed to illustrate damage to a person’s lungs, which means that the correct classification and scoring of a patient’s sonogram can be used to assess lung involvement.Methods: The purpose of this study was to establish a lung involvement assessment model based on deep learning. A novel multimodal channel and receptive field attention network combined with R… Show more
“…(5) Several studies have shown that LUS can detect interstitial disease, subpleural consolidations, and respiratory distress of any aetiology, with sensitivity and specificity superior to chest radiography and comparable to CT. (6)(7)(8) Indeed, LUS has already been recommended in past viral pandemics (9) and growing evidence demonstrates its effectiveness in patients with COVID-19, (10) which allows identifying the degree of lung involvement, its course, and the possible association between the initial lung involvement and its prognosis. (11)(12)(13)(14)(15) Our objective was to evaluate the performance of LUS through the lung ultrasound score (LUS score) to determine the severity of pneumonia and the short-term outcomes of patients with COVID-19 admitted to the intensive care unit. We hypothesize that the Lung Ultrasound Score (LUS) correlates with clinical evolution and predicts mortality in critically ill COVID-19 pneumonia patients.…”
Objective: To evaluate the performance of lung ultrasound to determine short-term outcomes of patients with COVID-19 admitted to the intensive care unit. Methods: This is a Prospective, observational study. Between July and November 2020, 59 patients were included and underwent at least two LUS assessments using LUS score (range 0-42) on day of admission, day 5th, and 10th of admission. Results: Age was 66.5±15 years, APACHE II was 8.3±3.9, 12 (20%) patients had malignancy, 46 (78%) patients had a non-invasive ventilation/high-flow nasal cannula and 38 (64%) patients required mechanical ventilation. The median stay in ICU was 12 days (IQR 8.5-20.5 days). ICU or hospital mortality was 54%. On admission, the LUS score was 20.8±6.1; on day 5th and day 10th of admission, scores were 27.6±5.5 and 29.4±5.3, respectively (P=0.007). As clinical condition deteriorated the LUS score increased, with a positive correlation of 0.52, P <0.001. Patients with worse LUS on day 5th versus better score had a mortality of 76% versus 33% (OR 6.29, 95%CI 2.01-19.65, p. 0.003); a similar difference was observed on day 10. LUS score of 5th day of admission had an area under the curve of 0.80, best cut-point of 27, sensitivity and specificity of 0.75 and 0.78 respectively. Conclusion: These findings position LUS as a simple and reproducible method to predict the course of COVID-19 patients.
“…(5) Several studies have shown that LUS can detect interstitial disease, subpleural consolidations, and respiratory distress of any aetiology, with sensitivity and specificity superior to chest radiography and comparable to CT. (6)(7)(8) Indeed, LUS has already been recommended in past viral pandemics (9) and growing evidence demonstrates its effectiveness in patients with COVID-19, (10) which allows identifying the degree of lung involvement, its course, and the possible association between the initial lung involvement and its prognosis. (11)(12)(13)(14)(15) Our objective was to evaluate the performance of LUS through the lung ultrasound score (LUS score) to determine the severity of pneumonia and the short-term outcomes of patients with COVID-19 admitted to the intensive care unit. We hypothesize that the Lung Ultrasound Score (LUS) correlates with clinical evolution and predicts mortality in critically ill COVID-19 pneumonia patients.…”
Objective: To evaluate the performance of lung ultrasound to determine short-term outcomes of patients with COVID-19 admitted to the intensive care unit. Methods: This is a Prospective, observational study. Between July and November 2020, 59 patients were included and underwent at least two LUS assessments using LUS score (range 0-42) on day of admission, day 5th, and 10th of admission. Results: Age was 66.5±15 years, APACHE II was 8.3±3.9, 12 (20%) patients had malignancy, 46 (78%) patients had a non-invasive ventilation/high-flow nasal cannula and 38 (64%) patients required mechanical ventilation. The median stay in ICU was 12 days (IQR 8.5-20.5 days). ICU or hospital mortality was 54%. On admission, the LUS score was 20.8±6.1; on day 5th and day 10th of admission, scores were 27.6±5.5 and 29.4±5.3, respectively (P=0.007). As clinical condition deteriorated the LUS score increased, with a positive correlation of 0.52, P <0.001. Patients with worse LUS on day 5th versus better score had a mortality of 76% versus 33% (OR 6.29, 95%CI 2.01-19.65, p. 0.003); a similar difference was observed on day 10. LUS score of 5th day of admission had an area under the curve of 0.80, best cut-point of 27, sensitivity and specificity of 0.75 and 0.78 respectively. Conclusion: These findings position LUS as a simple and reproducible method to predict the course of COVID-19 patients.
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