2020
DOI: 10.1016/j.ijpharm.2020.119336
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Evaluation of lipid nanoparticles for topical delivery of protocatechuic acid and ethyl protocatechuate as a new photoprotection strategy

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Cited by 16 publications
(5 citation statements)
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“… Boakye et al., 2016 Prevention Liposome P0 P2 SLN, nanostructured lipid carrier NLCs showed the ability for controlled release and protective effects against UVB-mediated degradation of P0 and P2. Daré et al., 2020 Prevention Liposome Quercetin Nanostructured lipid carriers Use of NLCs with quercetin in the developed photoprotective formulation significantly increased in vivo SPF without changing the number of UV filters. Exhibited improved effect on skin barrier hydration.…”
Section: Nps In Skin Cancer Preventionmentioning
confidence: 99%
See 1 more Smart Citation
“… Boakye et al., 2016 Prevention Liposome P0 P2 SLN, nanostructured lipid carrier NLCs showed the ability for controlled release and protective effects against UVB-mediated degradation of P0 and P2. Daré et al., 2020 Prevention Liposome Quercetin Nanostructured lipid carriers Use of NLCs with quercetin in the developed photoprotective formulation significantly increased in vivo SPF without changing the number of UV filters. Exhibited improved effect on skin barrier hydration.…”
Section: Nps In Skin Cancer Preventionmentioning
confidence: 99%
“…NLCs, as described previously, evolved from SLNs in pursuit of improved encapsulation efficiency and stability in addition to decreased cytotoxicity ( Daré et al., 2020 ; Felippim et al., 2020 ). NLCs have been shown to enhance sunscreen photostability and reduce skin irritation ( Damiani and Puglia, 2019 ; Durand et al., 2010 ; Puglia et al., 2012 ; Suh et al., 2019 ).…”
Section: Nps In Skin Cancer Preventionmentioning
confidence: 99%
“…Nanotechnology-based drug delivery strategies constitute a potential approach to enhance the poor bioavailability of berberine. Many studies have demonstrated that topical delivery has the characteristics of targeting and performance release controllability, which plays an important role in medical treatment ( Dare et al, 2020 ). Among them, intranasal delivery, as a form of topical delivery, bypasses the blood–brain barrier through the olfactory pathway and trigeminal nerve pathway, directly transporting drugs to the brain ( Dhuria et al, 2010 ).…”
Section: Challenges and Possible Solutionsmentioning
confidence: 99%
“…This structure determines their higher drug-loading ability (compared to solid lipid nanoparticles) and improved drug retention [10]. Various phenolic compounds have been encapsulated in NLCs, thereby obtaining enhanced solubility of the APIs (ellagic acid NLCs), reduced skin irritation and photoprotection (protocatechuic acid NLCs), and improved skin penetration and bioavailability (resveratrol NLCs) [11][12][13]. Nevertheless, the topical effects of NLCs may be further improved when sufficient skin contact time is provided, e.g., through their inclusion in a semisolid vehicle.…”
Section: Introductionmentioning
confidence: 99%