2018
DOI: 10.4103/apc.apc_75_17
|View full text |Cite
|
Sign up to set email alerts
|

Evaluation of left ventricular function in obese children without hypertension by a tissue Doppler imaging study

Abstract: Background:The prevalence of obesity is increasing worldwide. Obese children without hypertension are becoming an important health challenge.Aims:Complications of obesity in adults are well established, but in obese children, cardiac dysfunction has not been reported clinically.Settings and Design:The present crosssectional study investigates subclinical systolic and diastolic dysfunction using echocardiographic modalities.Materials and Methods:Twentyfive youngsters with body mass index (BMI) >30 and 25 health… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

1
7
0

Year Published

2018
2018
2022
2022

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 9 publications
(8 citation statements)
references
References 16 publications
1
7
0
Order By: Relevance
“…Significant differences in diastolic function between groups, expressed by lower E/A ratio and higher E/e', emerged in accordance with previous studies [21,22,52]. The ratio of peak early and late transmitral flow velocities E/A, correlated significantly with WHtR ratio and hs-CRP, but not with left ventricular mass like previously shown [53].…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…Significant differences in diastolic function between groups, expressed by lower E/A ratio and higher E/e', emerged in accordance with previous studies [21,22,52]. The ratio of peak early and late transmitral flow velocities E/A, correlated significantly with WHtR ratio and hs-CRP, but not with left ventricular mass like previously shown [53].…”
Section: Discussionsupporting
confidence: 90%
“…Lambobarda et al found no significant difference in E/e' ratio between obese children and lean controls [17] and the same applies to the study of Barbosa et al in which only higher velocities a' of mitral annulus in late diastole were recorded [63]. On the contrary, Ghandi et al reported a statistically significant dampening in E/e' in the case group [52]. In the present study, E/e' ratio was significantly higher in the obese group in accordance to previous studies [22,53,64] and correlated significantly with WHR, skinfold and uric acid levels when both groups were considered together.…”
Section: Discussionmentioning
confidence: 82%
“…In our study, the anemic obese group was found to have significantly higher cardiac pulse rates than the nonanemic obese group, even though the anemia was mild. The changes in E- and A-waves seen in PWD might be caused by increased heart rates in our anemic obese group, which may be indicative of early subclinical ventricular diastolic dysfunction [ 21 , 23 , 25 , 26 ].…”
Section: Discussionmentioning
confidence: 99%
“…Sharpe et al [ 27 ] demonstrated that BMI is directly related to LVMI. An increased LVMI results in ventricular hypertrophy, which eventually results in left ventricular diastolic dysfunction [ 23 , 25 , 26 , 27 , 28 , 29 , 30 ]. Similarly, in our study, measurements of LVM, LVMI, LVPWDD, and IVSDD were found to be increased in both obese groups compared to the healthy control group.…”
Section: Discussionmentioning
confidence: 99%
“…[2][3][4] However, a number of studies demonstrated normal systolic function in obese participants. 5,6 Recently, we also found normal left ventricular ejection fraction (LVEF) and fractional shortening (FS) with altered cardiac morphologic indices in obese adolescents. 7 This discrepancy is probably because the stages of cardiac dysfunction are differentially affected by the severity and duration of obesity.…”
Section: Introductionmentioning
confidence: 97%