Evaluation of left atrial functions by color tissue Doppler imaging in adults with body mass indexes ≥30 kg/m2 versus those &lt;30 kg/m2

Gülel, Okan; Yüksel, Serkan; Soylu, Korhan; Kaplan, Özgür; Yılmaz, Özcan; Kahraman, Hakkı; Şahin, Mahmut

doi:10.1007/s10554-008-9403-4

Cited by 20 publications

(13 citation statements)

References 25 publications

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“…347,348 In most studies, noninvasive ejection indices such as LV fractional shortening and LVEF have been reported for assessment of LV function in obesity. [348][349][350][351][352][353][354] Even in studies in which LV systolic function was lower in obese than in lean patients, LV ejection phase indices usually remained within the normal range or were mildly impaired in the majority of those with depressed values. [347][348][349][350] In contrast, some studies also found supranormal LV systolic function in obese subjects.…”

Section: Endocrine/metabolic Causes Obesity Cardiomyopathymentioning

confidence: 99%

Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association

Bozkurt¹,

Colvin²,

Cook³

et al. 2016

Circulation

603

663

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CLINICAL STATEMENTS AND GUIDELINEST he intent of this American Heart Association (AHA) scientific statement is to summarize our current understanding of dilated cardiomyopathies. There is special emphasis on recent developments in diagnostic approaches and therapies for specific cardiomyopathies. Recommendations in this document are based on published studies, published practice guidelines from the American College of Cardiology (ACC)/AHA 1 and other organizations, 2,3 and the multidisciplinary expertise of the writing group. Existing evidence in epidemiology, classification, diagnosis, and management of specific cardiomyopathies is usually derived from nonrandomized observational studies, registries, case reports, or expert opinion based on clinical experience, not large-scale randomized clinical trials or systematic reviews. Therefore, in this document, rather than using the standard ACC/AHA classification schema of recommendations and level of evidence, 4 we have included key management strategies at the end of each section and categorized our recommendations according to the level of consensus. Although the format of our recommendations might resemble the ACC/AHA classification of recommendations used in the ACC/AHA practice guidelines, because of the preponderance of expert opinion or level of evidence C evidence in our document, we elected to use different terminology to provide a distinction from the practice guidelines, in which stronger levels and quality of evidence with randomized clinical trials or meta-analyses are usually present. 4 The levels of evidence follow the AHA and ACC methods of classifying the level of certainty of the treatment effect. 4 DEfINITIoN of DILATED CArDIoMyopAThyThe term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of hypertension, valvular, congenital, or ischemic heart disease. 5 In clinical practice, the pathogenesis of heart failure (HF) has often been placed into 2 categories: ischemic and nonischemic cardiomyopathy. The term nonischemic cardiomyopathy has been interchangeably used with DCM. Although this approach might be practical, it fails to recognize that nonischemic cardiomyopathy can include cardiomyopathies caused by volume or pressure overload (such as hypertension or valvular heart disease) that are not conventionally accepted under the definition of DCM. 1,5 Again, in general practice and clinical research trials, the term ischemic cardiomyopathy is defined as cardiomyopathy caused by ischemic heart disease. Current use of ischemic cardiomyopathy terminology implies ventricular dilation and depressed myocardial contractility caused by ischemia or infarction. CLASSIfICATIoN of CArDIoMyopAThIESThe first classification on this topic categorized cardiomyopathies as heart muscle diseases with dilated (DCM), hypertrophic, restrictive, arrhythmogenic right ventricular (ARVC), or nonclassifiable cardiomyopathy in 1980. 5 Subse...

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Section: Endocrine/metabolic Causes Obesity Cardiomyopathymentioning

confidence: 99%

Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association

Bozkurt¹,

Colvin²,

Cook³

et al. 2016

Circulation

603

663

View full text Add to dashboard Cite

show abstract

“…In the present study, tissue Doppler imaging was used to assess LA peak systolic and late diastolic strain, which represent LA reservoir function and LA booster pump function, respectively (22). At baseline, LA strain was impaired as compared with previously reported values for healthy controls (23,24). LA reservoir function is determined mainly by LV systolic function and LA wall stiffness (25).…”

Section: Discussionmentioning

confidence: 76%

Left Atrial Strain Predicts Reverse Remodeling After Catheter Ablation for Atrial Fibrillation

Tops

Delgado

Bertini

et al. 2011

Journal of the American College of Cardiology

172

134

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“…LVDD is common in the obese population and is associated with an adverse cardiovascular prognosis, related to changes in cardiac structure and function associated with hemodynamic volume overload (19, 20). Powell et al (21) associated obesity with impaired LV relaxation and elevated LV diastolic filling pressures.…”

Section: Discussionmentioning

confidence: 99%

Mitral annular plane systolic excursion in the assessment of left ventricular diastolic dysfunction in obese adults

Taşolar

Mete

Çetın³

et al. 2015

Anatol J Cardiol

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Objective:Mitral annular plane systolic excursion (MAPSE) is a simple way to assess left ventricle (LV) function. MAPSE is also correlated to parameters, illustrating the close relation between systolic and diastolic function of LV. In this study, we evaluated whether MAPSE could help us in the determination the LV diastolic dysfunction (DD) in obese adults.Methods:Our study was a prospective cross-sectional study. Obese patients who were referred from the endocrinology clinic were enrolled into this study. The participants included 40 obese patients with early-stage DD (grade I and II) and 40 obese patients with normal diastolic function, with an equal number of males and females. The patients with DD were further divided into Obese DD+I, who had grade I DD, and Obese DD+II, who had grade II DD. Student t-test, Mann-Whitney U test, one-way analysis of variance, ROC curve analysis, and pairwise comparisons of the ROC curves were used for statistical analysis.Results:MAPSE was different in all groups, with the lowest value in the Obese DD+II group (p<0.001). E/Em ratio was also different among all groups and was highest in the Obese DD+II group (p<0.001). Furthermore, MAPSE was negatively correlated with E/Em ratio (r=-0.368, p=0.020). The optimal threshold point of MAPSE in the diagnosis of left ventricle diastolic dysfunction (LVDD) was ≥1.45 cm, with 92.5% sensitivity (95% CI 79.6-98.4) and 77.5% specificity (95% CI 61.5-89.2) in the ROC curve analysis. There was no difference in the pairwise comparisons of the ROC curves of MAPSE and E/Em ratio in the diagnosis of DD [area under the ROC curve 0.902 (0.033) vs. 0.927 (0.027); p=0.54].Conclusion:Consequently, we found significantly a close relationship between MAPSE with conventional echocardiographic parameters, especially with E/Em, in the detection of left ventricle diastolic dysfunction (LVDD) in obese adults with normal LV ejection fraction. We think that MAPSE is a simple, easily acquired and less time consuming measurement and may help us in the stratification of LVDD in obese adults.

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Evaluation of left atrial functions by color tissue Doppler imaging in adults with body mass indexes ≥30 kg/m2 versus those <30 kg/m2

Cited by 20 publications

References 25 publications

Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association

Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association

Left Atrial Strain Predicts Reverse Remodeling After Catheter Ablation for Atrial Fibrillation

Mitral annular plane systolic excursion in the assessment of left ventricular diastolic dysfunction in obese adults

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