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DHHS (NIOSH) Publication No. 2012-147
May 2012
Safer • Healthier • People
TM
General Safe Practices for Working with Engineered Nanomaterials in Research Laboratoriesiii
ForewordThe National Institute for Occupational Safety and Health (NIOSH) is pleased to present General Safe Practices for Working with Engineered Nanomaterials in Research Laboratories. Engineered nanomaterial applications are rapidly expanding throughout the United States and worldwide. The research community is at the front line of creating these new nanomaterials, testing their usefulness in a variety of applications, and determining their toxicological and environmental impacts.With the publication of this document, NIOSH hopes to raise awareness of the occupational safety and health practices that should be followed during the synthesis, characterization, and experimentation with engineered nanomaterials in a laboratory setting. The document contains recommendations on engineering controls and safe practices for handling engineered nanomaterials in laboratories and some pilot scale operations. This guidance was designed to be used in tandem with well-established practices and the laboratory's chemical hygiene plan. As our knowledge of nanotechnology increases, so too will our efforts to provide additional guidance materials for working safely with engineered nanomaterials.
AcknowledgmentsThis document is based on input from several subject matter experts and was initiated as a joint effort under a Memorandum of Understanding between NIOSH and the Center for High-rate Nanomanufacturing (CHN). Some of the specific content was derived from a report generated by Michael Ellenbecker and Su-Jung (Candace) Tsai at the University of Massachusetts Lowell (UMass Lowell), one of the CHN member campuses, and was supported by a contract from the NIOSH Nanotechnology Research Center (NTRC). Paul Schulte is the manager and Charles Geraci is the coordinator of the NIOSH nanotechnology cross-sector program. Special thanks go to Catherine Beaucham and Laura Hodson for writing and organizing this report. Others who contributed substantially to the writing and research include Mark Hoover and Ralph Zumwalde.
Executive SummaryNanotechnology, the manipulation of matter at a nanometer scale to produce new materials, structures, and devices having new properties, may revolutionize life in the future. It has the potential to impact medicine through improved disease diagnosis and treatment technologies and to impact manufacturing by creating smaller, lighter, stronger, and more efficient products. Nanotechnology could potentially decrease the impact of pollution by improving methods for water purification or energy conservation....