Evaluation of intracanal acetazolamide in late reimplanted rat teeth

Abstract

Objective:The aim of this study was to evaluate the use of acetazolamide combined with different agents as intracanal medication in late reimplanted rat teeth.Materials and Methods:In 100 Wistar rats, divided into 5 groups of 20, one of the following medications was used: Acetazolamide liquid (AL); AL with calcium hydroxide powder (ALHC); acetazolamide powder with AL; acetazolamide powder with physiological solution; and calcium hydroxide with physiological solution (control). At 30 and 60 days after reimplantation, the animals were sacrificed, tissues were processed, and cuts were stained with hematoxylin and eosin. An optical microscope was used to determine the following: percentage of inflammatory root resorption (RRI); percentage of substitute root resorption (RRS); and presence of ankylosis. The data obtained was submitted for statistical analysis.Results:Group ALHC had a significantly higher RRS than the control group at 60 days (P = 0.01). Group AL showed significantly less ankylosis than the other groups, including the control, at 30 days. AL showed results similar to those of the control group with respect to RRS.Conclusion:Acetazolamide has the potential to be an effective intracanal medication.

Demystifying the Treatment of Teeth with Inflammatory External Root Resorption, According To the Pulpar Condition

“…The main cause is dental traumatism [4]. Although several therapeutic alternatives are being tested in an attempt to prevent or slow down the substitution resorption process, it has not yet been possible to terminate the process when established [1][2][3]5]. The treatment of external inflammatory root resorptions consists basically in the removal of its cause.…”

Qualitative Histological Evaluation of Various Decalcifying Agents on Human Dental Tissue

“…Histological examination of dental hard tissue and dental pulp is essential for establishing the diagnosis of pulpal diseases, developmental disorders, forensic odontology, and dental research. [1][2][3][4] To obtain thin sections, conventional tissue processing methods are not possible for the hard tissue such as bone, teeth, and calcified lesions. Decalcification, a process of removing calcium from hard tissue, is routinely conducted in all histological and histopathological laboratories to make the tissue soft enough to be cut by the microtome.…”