Evaluation of Innovative Skin-Marking Technique Performed Before Thyroid Ultrasound-Guided Fine-Needle Aspiration Biopsies

Brenta, Gabriela; Schnitman, Marta; Bonnahon, Lia; Besuschio, Santiago; Zuk, Carlos; Barrio, G.; Peruzzotti, Cesar; Saubidet, Gustavo

doi:10.4158/ep.8.1.5

Cited by 35 publications

(8 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Validation of this procedure by cytohistological correlation in our institution was previously reported [13]. In the present series, 46 subjects were referred to surgery and cancer was confirmed in 20 of them (43%).…”

Section: Methodssupporting

confidence: 61%

“…US-guided FNABs were carried out by one of the three operators of our institution, each having more than 15 years of experience with this procedure. In some patients in whom it was difficult to place the probe due to the shape of the neck, the skin-marking technique was employed to perform FNAB [13]. At least 2–6 needle passages were performed in each nodule.…”

Section: Methodsmentioning

confidence: 99%

“…Therefore, we continued using our former classification. Accordingly, results were classified as benign, insufficient, indeterminate, and malignant [13]. Results suspicious of papillary thyroid cancer were included in the malignant category.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Differential Profile of Ultrasound Findings Associated with Malignancy in Mixed and Solid Thyroid Nodules in an Elderly Female Population

Vera

Meroño²,

Urrutia

et al. 2014

Journal of Thyroid Research

Self Cite

View full text Add to dashboard Cite

Objective. Ultrasonographic characteristics are associated with thyroid malignancy. Our aim was to compare the diagnostic value of ultrasound features in the detection of thyroid malignancy in both solid and mixed nodules. Methods. We prospectively studied female patients (≥50 years) referred to ultrasound-guided fine needle aspiration biopsy. Ultrasound features considered suspicious were hypoechogenicity, microcalcifications, irregular margins, high anteroposterior (AP)/axial-ratio, and absent halo. Associations were separately assessed in mixed and solid nodules. Results. In a group of 504 elderly female patients (age = 69 ± 8 years), the frequency of malignant cytology was 6%. Thirty-one percent of nodules were mixed and 60% were solid. The rate of malignant cytology was similar for mixed and solid nodules (7.4 versus 5.8%, P: 0.56). While in mixed nodules none of the ultrasound characteristics were associated with malignant cytology, in solid nodules irregular margins and microcalcifications were significant (all P < 0.05). The combination of irregular margins and/or microcalcifications significantly increased the association with malignant cytology only in solid nodules (OR: 2.76 (95% CI: 1.25–6.10), P: 0.012). Conclusions. Ultrasound features were of poor diagnostic value in mixed nodules, which harbored malignant lesions as often as solid nodules. Our findings challenge the recommended minimal size for ultrasound-guided fine needle aspiration biopsy in mixed nodules.

show abstract

Section: Methodssupporting

confidence: 61%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Differential Profile of Ultrasound Findings Associated with Malignancy in Mixed and Solid Thyroid Nodules in an Elderly Female Population

Vera

Meroño²,

Urrutia

et al. 2014

Journal of Thyroid Research

Self Cite

View full text Add to dashboard Cite

show abstract

“…Measuring PPG levels may help identify when to treat patients who have HbA 1c levels that are borderline high due to postprandial hyperglycemia. Accordingly, both the AACE and ACE recommend treating to a 2-hour PPG target of <140 mg/dL (<7.8 mmol/L) 130. As patients approach target HbA 1c levels, PPG levels may contribute more to HbA 1c than FPG levels.…”

Section: Resultsmentioning

confidence: 99%

Identifying and meeting the challenges of insulin therapy in type 2 diabetes

Sorli¹,

Heile²

2014

JMDH

View full text Add to dashboard Cite

Type 2 diabetes mellitus (T2DM) is a chronic illness that requires clinical recognition and treatment of the dual pathophysiologic entities of altered glycemic control and insulin resistance to reduce the risk of long-term micro- and macrovascular complications. Although insulin is one of the most effective and widely used therapeutic options in the management of diabetes, it is used by less than one-half of patients for whom it is recommended. Clinician-, patient-, and health care system-related challenges present numerous obstacles to insulin use in T2DM. Clinicians must remain informed about new insulin products, emerging technologies, and treatment options that have the potential to improve adherence to insulin therapy while optimizing glycemic control and mitigating the risks of therapy. Patient-related challenges may be overcome by actively listening to the patient’s fears and concerns regarding insulin therapy and by educating patients about the importance, rationale, and evolving role of insulin in individualized self-treatment regimens. Enlisting the services of Certified Diabetes Educators and office personnel can help in addressing patient-related challenges. Self-management of diabetes requires improved patient awareness regarding the importance of lifestyle modifications, self-monitoring, and/or continuous glucose monitoring, improved methods of insulin delivery (eg, insulin pens), and the enhanced convenience and safety provided by insulin analogs. Health care system-related challenges may be improved through control of the rising cost of insulin therapy while making it available to patients. To increase the success rate of treatment of T2DM, the 2012 position statement from the American Diabetes Association and the European Association for the Study of Diabetes focused on individualized patient care and provided clinicians with general treatment goals, implementation strategies, and tools to evaluate the quality of care.

show abstract

“…Fasting plasma glucose (as per American Diabetes Association)Normal-<5.6 mmol/l (100 mg/dl)Impaired glucose tolerance: 5.6-6.9 mmol/l (100-125 mg/dl)Diabetes mellitus - ≥7 mmol/l (126 mg/dl)[16]HbA1c: normal levelNormal - <6.5[17–19] …”

Section: Methodsmentioning

confidence: 99%

Patterns of glycemic control using glycosylated hemoglobin in diabetics

Kahlon

Pathak

2011

J Pharm Bioall Sci

View full text Add to dashboard Cite

Aim:Till now estimation of blood glucose is the highly effective method for diagnosing diabetes mellitus but it provides a short-term picture of control. More evidence is required to prove that plasma glucose and glycosylated hemoglobin levels together gives a better estimate of glycemic control and compliance with treatment. Indian diabetes risk score (IDRS) is a simplified screening tool for identifying undiagnosed diabetic subjects, requires minimum time, and effort and can help to considerably reduce the costs of screening.Objective:To study patterns of glycemic control using glycosylated hemoglobin in diabetic patients. To find out correlation between levels of plasma glucose and glycosylated hemoglobin in diabetics and to calculate IDRS of the study population.Materials and Methods:A cross sectional study was conducted among 300 known diabetic patients attending outpatient department of a rural medical college in Haryana, India. Following standard procedures and protocols FPG and glycosylated hemoglobin were measured to find out a pattern of glycemic control in them after taking their written and informed consent. A correlation between the levels of glycosylated hemoglobin and fasting blood glucose was also calculated. These patients were made to fill a performa and their demographic and clinical risk factors were noted and based on this, their IDRS was calculated. This was done to validate the IDRS in Indian rural population.Results:Fifty-two percent of the population had fasting plasma glucose level between 125-150 mg/dl, 21% had this level between 151-175 mg/dl. Thirteen percent of the study subjects had HbA1C between 6.5-7.5, more than half (57.3%) had this value between 7.5-8.5, 12% and 18% had values between 8.5-9.5 and 9.5-10.5, respectively. Twelve percent of the participants had HbA1C level higher than 10.5. Correlation of fasting plasma glucose level and HbA1C was also studied and found that correlation coefficient came out to be .311. This correlation was found to be statistically significant (P = .007). Sixty-five percent of the case had IDRS higher than 60.Conclusions:Glycaemic control in diabetics can be better assessed with glycosylated hemoglobin and FPG together. A positive correlation between FPG and HbA1c allows for the use of HbA1c along with FPG in diagnosing type 2 DM but the two should not be used interchangeably. IDRS can be used as a screening tool for diabetes.

show abstract

Evaluation of Innovative Skin-Marking Technique Performed Before Thyroid Ultrasound-Guided Fine-Needle Aspiration Biopsies

Cited by 35 publications

References 7 publications

Differential Profile of Ultrasound Findings Associated with Malignancy in Mixed and Solid Thyroid Nodules in an Elderly Female Population

Differential Profile of Ultrasound Findings Associated with Malignancy in Mixed and Solid Thyroid Nodules in an Elderly Female Population

Identifying and meeting the challenges of insulin therapy in type 2 diabetes

Patterns of glycemic control using glycosylated hemoglobin in diabetics

Contact Info

Product

Resources

About