Evaluation of Inhaler Technique and Patient Satisfaction With Fixed-Combination Budesonide/Formoterol Dry-Powder Inhaler in Chronic Obstructive Pulmonary Disease (COPD): Data on Real-Life Clinical Practice in Turkey

Öztürk, Can; Kaya, Akın; Bilgin, Cahit; Yücesoy, Leyla; Ikidag, Belgin; Demirel, Mustafa; Başlılar, Şeyma; Şaylan, Bengü; Senol, Tuncer; Ağanoğlu, Semih; Can, Gonca; Doğrul, Mustafa Ilgaz; Çam, Murat; Erdogan, Nezaket; Batum, Özgür; Turan, Muzaffer Onur; Demir, Cahit; Torun, Şerife; Cirit, Murat; Turan, Mustafa; Keleşoğlu, Arif; Yaşar, Savaş; Uzunay, Oznur; Melek, Kevser; Altiparmak, Osman

doi:10.1378/chest.1688796

Cited by 5 publications

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“…Of 33 studies which examined the effect of patient age [ 10 , 26 , 30 , 33 , 34 , 38 , 40 , 44 , 48 , 53 , 55 – 77 ], 29 were in adults and 4 were paediatric. Only twelve studies (36%) reported age to be significantly associated with worsening frequency of inhaler errors [ 10 , 26 , 30 , 44 , 53 , 57 , 60 , 64 , 66 , 69 , 72 , 73 ], whereas 21 studies found no significant association. In 7 studies, older adults were found to make significantly more errors [ 10 , 30 , 44 , 57 , 60 , 64 , 66 ].…”

Section: Resultsmentioning

confidence: 99%

“…Only twelve studies (36%) reported age to be significantly associated with worsening frequency of inhaler errors [ 10 , 26 , 30 , 44 , 53 , 57 , 60 , 64 , 66 , 69 , 72 , 73 ], whereas 21 studies found no significant association. In 7 studies, older adults were found to make significantly more errors [ 10 , 30 , 44 , 57 , 60 , 64 , 66 ]. Of the 4 paediatric studies [ 26 , 40 , 53 , 74 ], two reported a significant association between age and frequency of errors: Deerojanawong reported that younger children made errors significantly more frequently [ 26 ], while Capanoglu reported the opposite finding: that older children made errors more frequently [ 53 ].…”

Section: Resultsmentioning

confidence: 99%

“…Twenty-five studies of 114 (22%) reported on the effects of gender [ 10 , 30 , 34 , 38 , 40 , 44 , 48 , 53 , 55 , 56 , 59 – 61 , 63 , 65 – 67 , 70 , 73 , 74 , 76 – 80 ], where 6 studies concluded a significant impact on inhaler error frequency, but the results were contradictory and inconclusive as to whether male or female gender was associated with poor technique [ 48 , 53 , 60 , 66 , 79 , 80 ]. Of the 22 studies that reported a trend between low education and high inhaler error frequency [ 10 , 34 , 38 , 44 , 48 , 53 , 56 , 59 – 62 , 64 – 67 , 70 , 73 – 76 , 80 , 81 ], 10 found the association to be statistically significant [ 10 , 34 , 48 , 53 , 56 , 60 , 62 , 66 , 73 , 80 ].…”

Section: Resultsmentioning

confidence: 99%

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Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes

et al. 2018

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BackgroundInhaled drug delivery is the cornerstone treatment for asthma and chronic obstructive pulmonary disease (COPD). However, use of inhaler devices can be challenging, potentially leading to critical errors in handling that can significantly reduce drug delivery to the lungs and effectiveness of treatment.MethodsA systematic review was conducted to define ‘critical’ errors and their impact on health outcomes and resource use between 2004 and 2016, using key search terms for inhaler errors in asthma and COPD (Search-1) and associated health-economic and patient burden (Search-2).ResultsSearch-1 identified 62 manuscripts, 47 abstracts, and 5 conference proceedings (n = 114 total). Search-2 identified 9 studies. We observed 299 descriptions of critical error. Age, education status, previous inhaler instruction, comorbidities and socioeconomic status were associated with worse handling error frequency. A significant association was found between inhaler errors and poor disease outcomes (exacerbations), and greater health-economic burden.ConclusionsWe have shown wide variations in how critical errors are defined, and the evidence shows an important association between inhaler errors and worsened health outcomes. Given the negative impact diminished disease outcomes impose on resource use, our findings highlight the importance of achieving optimal inhaler technique, and a need for a consensus on defining critical and non-critical errors.Electronic supplementary materialThe online version of this article (10.1186/s12931-017-0710-y) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes

et al. 2018

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“…The results revealed that the majority of patients were able to use TH, whereas older age was associated with higher rate of errors in inhalation maneuvers, while the majority of patients were satisfied with the overall use of the device. 25 …”

Section: Discussionmentioning

confidence: 99%

“…In addition, the study included patients >18 years of age, so further studies to investigate the patient satisfaction in pediatric and adolescent asthma patients could be warranted. Nevertheless, evaluations across patients with asthma and COPD, deriving from diverse ethnic and cultural background, 17 , 25 led us to the conclusion that the FSI-10 is a reliable, practical, and responsive instrument for measuring inhalation device satisfaction.…”

Section: Discussionmentioning

confidence: 99%

Assessment of satisfaction with different dry powder inhalation devices in Greek patients with COPD and asthma: the ANASA study

Ζervas¹,

Samitas²,

Gaga³

2016

COPD

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BackgroundPoor adherence to inhaled therapy is common in patients with asthma and COPD. An inhaler selection based on patients’ preference could be beneficial to adherence and treatment effectiveness. Properly designed questionnaires can assess patients’ satisfaction with their medication devices. The aim of this study was to estimate, using the Feeling of Satisfaction with Inhaler (FSI-10) questionnaire, the ease of use and satisfaction of patients regarding three different marketed dry powder inhalers (DPIs): Diskus® (DK), Elpenhaler® (EH), and Turbuhaler® (TH). The FSI-10 is a self-completed questionnaire to assess patients’ opinions regarding ease of use, portability, and usability of devices, irrespective of the drug used.Patients and methodsWe performed a 4-week, open, noninterventional, multicenter, parallel clinical study in 560 asthmatic and 561 COPD patients. During the first visit, patients were classified into three groups according to the DPI they were already using. Patients were regularly receiving their treatments (Seretide DK, Rolenium EH, and Symbicort TH) and agreed to complete the FSI-10 questionnaire in the second visit.ResultsA total of 517 COPD and 523 asthma patients completed the study. All DPIs tested received satisfactory results, while the EH obtained consistently higher scores in the FSI-10 in both COPD and asthma patients (44.7 and 44.1 vs 41.5 and 43 for TH, 40.8 and 41.4 for DK, P<0.001 and P<0.01, respectively). TH was rated better than DK by asthma patients. Patients suffering with severe COPD tended to express higher feeling of satisfaction than those with moderate or mild disease, irrespective of the device used.ConclusionAll DPIs tested were highly acceptable by asthma and COPD patients of different ages; nevertheless, EH received significantly higher ratings in most of the questionnaire domains. COPD patients in advanced stages of the disease generally expressed higher level of satisfaction with their devices.

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Common errors in inhalation therapy: Impact and solutions

Rodríguez‐García

Barreiro

Muñoz

et al. 2020

Clinical Respiratory J

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Objective Inhalation therapy is one of the key pillars in the treatment of chronic obstructive diseases, such as asthma and COPD (Chronic obstructive pulmonary disease); however, wide number of errors occur with high frequency in the inhalation manoeuvres among these patient. This review discuss the main errors made with inhalation devices, factors associated with poor IT (inhalation technique), their consequences and possible solutions. Data sources To do this, we performed a search of any publications available in PubMed between the years 2000 and 2019, using the key words: asthma, COPD, obstructive lung disease, inhalers, misuse and errors. Study selections After a review of the titles and abstracts by the working group, the articles chosen were considered the most relevant in providing evidence of the problems and establishing solutions in the inhalation treatment of asthma and COPD. Results There are several publications that associated the errors in the inhalation technique with a poor prognosis both of asthma and COPD. Most authors generally agree in that a poor IT is associated with poor control of the symptoms. Conclusions It is essential to review the IT in all our patients with asthma and COPD due to the high socio‐economic impact that it involves; an effort must be made to homogenise the evaluation of IT, so that it helps to transmit a clear message to the patients, as well as to the health professionals on what is and what is not a correct manoeuvre.

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Evaluation of Inhaler Technique and Patient Satisfaction With Fixed-Combination Budesonide/Formoterol Dry-Powder Inhaler in Chronic Obstructive Pulmonary Disease (COPD): Data on Real-Life Clinical Practice in Turkey

Cited by 5 publications

References 0 publications

Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes

Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes

Assessment of satisfaction with different dry powder inhalation devices in Greek patients with COPD and asthma: the ANASA study

Common errors in inhalation therapy: Impact and solutions

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