Evaluation of infections in non-small cell lung cancer patients treated with radiotherapy

Sarıhan, Süreyya; Ercan, İlker; Saran, A.; Çetintaş, Sibel Kahraman; Akalın, Halis; Engin, K.

doi:10.1016/j.cdp.2004.11.001

Cited by 28 publications

(25 citation statements)

References 15 publications

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“…Many studies report that smoking cessation after a diagnosis of lung cancer is associated with health improvements (table 4) [64][65][66][67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83].…”

Section: Benefits Of Smoking Cessation In Patients With Lung Cancermentioning

confidence: 99%

Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit

Jiménez-Ruíz¹,

et al. 2015

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Chronic obstructive pulmonary disease (COPD), lung cancer, asthma and pulmonary tuberculosis are common pulmonary diseases that are caused or worsened by tobacco smoking. Growing observational evidence suggests that symptoms and prognosis of these conditions improve upon smoking cessation. Despite increasing numbers of (small) randomised controlled trials suggesting intensive smoking cessation treatments work in people with pulmonary diseases many patients are not given specific advice on the benefits or referred for intensive cessation treatments and, therefore, continue smoking. This is a qualitative review regarding smoking cessation in patients with COPD and other pulmonary disorders, written by a group of European Respiratory Society experts. We describe the epidemiological links between smoking and pulmonary disorders, the evidence for benefits of stopping smoking, how best to assess tobacco dependence and what interventions currently work best to help pulmonary patients quit. Finally, we describe characteristics and management of any "hardcore" smoker who finds it difficult to quit with standard approaches. @ERSpublications Smoking cessation is crucial for respiratory patients: every patient must be given advice and help to quit http://ow.ly/ITgsW

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Section: Benefits Of Smoking Cessation In Patients With Lung Cancermentioning

confidence: 99%

Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit

Jiménez-Ruíz¹,

et al. 2015

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“…The number of packages per year of cigarette smoking is significantly positively associated with infection in patients with NSCLC during radiotherapy [51]. Fox et al [7] found that, among NSCLC patients diagnosed with early stage disease, current smokers had a poorer prognosis for survival after radiation therapy.…”

Section: Benefits Of Smoking Cessation For Lung Cancer Patientsmentioning

confidence: 99%

Smoking Cessation: An Integral Part of Lung Cancer Treatment

Cataldo

Dubey²,

Prochaska³

2010

Oncology

164

131

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Lung cancer is the leading cause of cancer death in the US. About 50% of lung cancer patients are current smokers at the time of diagnosis and up to 83% continue to smoke after diagnosis. A recent study suggests that people who continue to smoke after a diagnosis of early-stage lung cancer almost double their risk of dying. Despite a growing body of evidence that continued smoking by patients after a lung cancer diagnosis is linked with less effective treatment and a poorer prognosis, the belief prevails that treating tobacco dependence is useless. With improved cancer treatments and survival rates, smoking cessation among lung cancer patients has become increasingly important. There is a pressing need to clarify the role of smoking cessation in the care of lung cancer patients. Objective: This paper will report on the benefits of smoking cessation for lung cancer patients and the elements of smoking cessation treatment, with consideration of tailoring to the needs of lung cancer patients. Results: Given the significant benefits of smoking cessation and that tobacco dependence remains a challenge for many lung cancer patients, cancer care providers need to offer full support and intensive treatment with a smoking cessation program that is tailored to lung cancer patients’ specific needs. Conclusion: A tobacco dependence treatment plan for lung cancer patients is provided.

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“…Informed consent was obtained from all patients. Pneumonia, including nosocomial pneumonia, is one of the main complications occurring in lung cancer patients due to defects in the clearance system in sites peripheral to the bronchial obstruction, or stenosis caused by cancer therapy as well as cancer itself and broad-spectrum antibiotics usage [7][8][9][10][11][12][13][14]. The role of anaerobes in the pathogenesis of pneumonia in hospitalized patients, especially in critically or chronically ill patients, is still controversial [4,15,16].…”

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confidence: 99%

Anaerobic bacteria colonizing the lower airways in lung cancer patients

Rybojad¹,

Łoś²,

Sawicki³

et al. 2011

Folia Histochem Cytobiol.

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Abstract:Abstract: Abstract: Abstract: Abstract: Anaerobes comprise most of the endogenous oropharyngeal microflora, and can cause infections of airways in lung cancer patients who are at high risk for respiratory tract infections. The aim of this study was to determine the frequency and species diversity of anaerobes in specimens from the lower airways of lung cancer patients. Sensitivity of the isolates to conventional antimicrobial agents used in anaerobe therapy was assessed. Respiratory secretions obtained by bronchoscopy from 30 lung cancer patients were cultured onto Wilkins--Chalgren agar in anaerobic conditions at 37°C for 72-96 hours. The isolates were identified using microtest Api 20A. The minimal inhibitory concentrations for penicillin G, amoxicillin/clavulanate, piperacillin/tazobactam, cefoxitin, imipenem, clindamycin, and metronidazole were determined by E-test. A total of 47 isolates of anaerobic bacteria were detected in 22 (73.3%) specimens. More than one species of anaerobe was found in 16 (53.3%) samples. The most frequently isolated were Actinomyces spp. and Peptostreptococcus spp., followed by Eubacterium lentum, Veillonella parvula, Prevotella spp., Bacteroides spp., Lactobacillus jensenii. Among antibiotics used in the study amoxicillin/clavulanate and imipenem were the most active in vitro (0% and 2% resistant strains, respectively). The highest resistance rate was found for penicillin G and metronidazole (36% and 38% resistant strains, respectively). The results obtained confirm the need to conduct analyses of anaerobic microflora colonizing the lower respiratory tract in patients with lung cancer to monitor potential etiologic factors of airways infections, as well as to propose efficient, empirical therapy. (Folia Histochemica et

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Evaluation of infections in non-small cell lung cancer patients treated with radiotherapy

Cited by 28 publications

References 15 publications

Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit

Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit

Smoking Cessation: An Integral Part of Lung Cancer Treatment

Anaerobic bacteria colonizing the lower airways in lung cancer patients

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