Evaluation of in vivo Anthelmintic Efficacy of Ethanolic Extract of Butea frondosa Seed against GI Parasites in Goats

Abstract

Background: The anthelmintic activity of Butea frondosa seed extract as an alternative to the synthetic anthelmintic against GIPs in goats was undertaken by studying EPG, body weight and hemato-biochemical parameters in the infested goats. Methods: Goats (n=18) found positive for parasitic infection by screening at Goat Research Station (GRS), AAU, Byrnihat were selected for the study. Two doses of ethanolic extract of Butea frondosa seed @ 100 mg/kg (Group A, n=6), @ 200 mg/kg (Group B, n=6) and Fentasplus @ 5 mg/kg body weight p. o. (Group C, n= 6) were given on 0th day and 14th day. Faecal and blood samples were collected at weekly intervals for a period of 42 days. Result: A significant decrease in the EPG count was noticed on 14th day post treatment. A significant increase in body weight and Hb, PCV, TEC, total serum protein, albumin, sodium, potassium, calcium, chloride, phosphorus and significant decrease in ESR, TLC, neutrophil, eosinophil count, AST, ALT and ALP were noticed post treatment. On the basis of reduction in EPG count and improvement in body weight and haemato-biochemical parameters, it is concluded that the ethanolic extracts of Butea frondosa seed @ 200 mg/kg body weight showed better result as anthelmintic in this study.