Evaluation of in vitro and in vivo anticancer activities of potassium koetjapate: a solubility improved formulation of koetjapic acid against human colon cancer
Seyedeh Fatemeh Jafari,
Maryam Keshavarzi,
Amin MalikShah AbdulMajid
et al.
Abstract:Background and purpose:
The previous work on koetjapic acid (KA) isolated from Sandoricum koetjape showed its efficacy towards colorectal cancer however KA has poor water solubility which poses the biggest hindrance to its efficacy. In the present paper, an attempt was made to study the anti-colon cancer efficacy of KA’s potassium salt i.e. potassium koetjapate (KKA) applying in vitro and in vivo methods.
Experimental approach:
KKA was produced by a sem… Show more
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