“Evaluation of I-PRF Injection Technique as an Alternative for Reconstruction of Interdental Papillae - A Pilot Study

Abstract

One of the most challenging and least predictable procedures in periodontal plastic surgery is the reconstruction of the lost interdental papilla. Preserving the integrity of the papillae is of utmost importance. Different variations of surgical procedures using connective tissue grafts have proved to be successful. Being less invasive in nature, non-surgical techniques such as hyaluronic acid injections have turned out to be a boon in this regard. Platelet concentrates like PRF & PRP have shown promising results when used in surgical reconstruction of the lost papilla. One of the recent advancements in PRF formulations is the injectable PRF which is a liquid concentrate encompassing higher leuckocyte numbers, which resulted in higher total growth factor release, requiring slower and shorter centrifugation speeds for preparation. i-PRF was shown to be a potent inducer of cell proliferation, migration and angiogenesis, inducer of higher broblast migration and expression of PDGF, TGF-β, and collagen,thereby playing a vital role in tissue regeneration. With the current understanding, this study was designed to investigate the efciency of iPRF in achieving interdental papillary enhancement. We have noted that mutilple doses of this autologous formulation prove to be a non-invasive alternative for the treatment of minimal interdental papilla loss; primarily Norland & Tarnow's Class I and to an extent Class II interdental papilla loss. Further validations of this technique are required