2023
DOI: 10.1002/mren.202300005
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Evaluation of Hyperthermic Potential and Acute Toxicity of PLGA‐PEG/Magnetite Microspheres Loaded with Oxaliplatin Using Mice as a Test System

Abstract: Oxaliplatin and modified magnetic nanoparticles (magnetite‐lysine) are inserted into microspheres of previously synthesized poly(lactic acid‐co‐glycolic acid‐b‐ethylene glycol) PLGA‐PEG to evaluate the in vitro hyperthermal potential and the acute toxicity in mice. The used nanoparticles are synthesized by the coprecipitation method, using Fe II and Fe III, and modification with lysine is performed during the synthesis. The drug and the magnetic nanoparticles are inserted into the polymer beads through oil in … Show more

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Cited by 3 publications
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