Evaluation of Hyperbaric Oxygen Therapy in the Treatment of Radiation-induced Hemorrhagic Cystitis

Yıldız, Hamza; Ercan, Erdinç; Demirer, Zafer

doi:10.1016/j.urology.2016.05.063

Cited by 2 publications

(2 citation statements)

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“…Different reports indicate session lengths vary between 60 and 120 minutes, sessions being once or twice a day, and delivery modalities for hyperbaric oxygen being masks, face‐tents, or within monoplace chambers attended with parents or caregivers . The ideal number of sessions would depend upon the respective degree of response, but a minimum of 20 sessions appears to prevent recurrence of symptoms . It is prudent to ensure absence of any aerobic microorganism–related infections and inherited clastogenic disorders such as Fanconi anemia in patients being considered for this treatment .…”

Section: Discussionmentioning

confidence: 99%

“…17 The ideal number of sessions would depend upon the respective degree of response, but a minimum of 20 sessions appears to prevent recurrence of symptoms. 34 It is prudent to ensure absence of any aerobic microorganism-related infections 28 and inherited clastogenic disorders such as Fanconi anemia in patients being considered for this treatment. 26 HBO2 increases the body ROI levels, and those susceptible to cellular DNA damage by these entities can manifest with tissue edema.…”

Section: Discussionmentioning

confidence: 99%

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Hyperbaric oxygen as a treatment modality in cyclophosphamide‐induced hemorrhagic cystitis

Kaur

Khan

Rodriguez

et al. 2018

Pediatric Transplantation

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Late-onset HC is a well-recognized complication associated with cyclophosphamide/acrolein-induced toxicity. It poses a management challenge when hyperhydration and bladder irrigation do not result in clinical improvement as desired. The data regarding use of hyperbaric oxygen therapy (HBO2) as an early treatment modality in this clinical setting are limited. We present 2 cases, that were refractory to hyperhydration and bladder irrigation but responded to HBO2. They were treated with 20-30 daily sessions over weekdays with 100% oxygen for 90 minutes at 2 atmospheric pressure units (2 atm). Both patients reported improved symptoms within the first 15 sessions, and hematuria diminished by 20 sessions. Hyperbaric oxygen is a less invasive, outpatient therapy that is effective for treatment of HC and is tolerated well by young patients.

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Section: Discussionmentioning

confidence: 99%