Background: Clinical specialists require access to the most recent and up to date professional information. However, barriers such as insufficient time and lack of necessary information retrieval skills necessitate the presence of clinical informationist (CI) in medical teams.Objectives: This study sought to determine the pre-requisite for CI participation in the grand round. Methods: This was a qualitative study carried out using content analysis approach. Study involved all fellowship students and attending physicians in the department of gastroenterology at Al-Zahra hospital in Isfahan (Iran), who were selected using purposive sampling. Gathered reports were analysed using qualitative content analysis and concept mapping approaches. Discussion: To improve the process of CI collaboration with clinical specialists during the educational rounds, it is necessary for CI to have certain pre-requisite skills. Conclusions: By identifying the pre-requisites for CI participation in the grand round and explaining advantages of this participation for clinical specialists, this study proposes a suitable process for implantation of CI participation in grand rounds.• Clinical informationists require an awareness of technical, organizational and structural infrastructure in order to meaningfully contribute to the clinical environment.