Evaluation of high-pitch dual-source CT angiography for evaluation of coronary and carotid-cerebrovascular arteries

Sun, Kai; Han, Ruijuan; Li, Wenhuan; Chen, Nan; Yang, Qi; Du, Xin; Wang, Chen; Liu, Guorong; Li, Yuechun; Zhou, Maorong; Liu, Ligang; Endt, Heidrun

doi:10.1016/j.ejrad.2014.11.009

Cited by 12 publications

(12 citation statements)

References 33 publications

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“…Increasing the injection rate could also shift the TDC to the left and up. According to the above adjustments, the present study improved the arterial attenuation when compared with those observed in previous studies (10–13); the contrast agent volume was reduced significantly in the present study.…”

Section: Discussionsupporting

confidence: 69%

“…Compared with 80 and 100 kVp, 70 kVp could reduce the radiation dose to 75 and 56%, respectively (15). Due to the improved equipment, the radiation dose of the one-step CTA in the present study was significantly lower than that used in previous studies by Sun et al (10) and Wang et al (11). One-step CTA has been pioneered and demonstrated in previous studies (10–11), but the present study has improved the low dose technique with the help of advantageous equipment.…”

Section: Discussionmentioning

confidence: 51%

“…High-pitch scanning has a very fast table-moving speed, which is due to the double tube-detector systems with gaps (8,9). In the present study, only ~700 msec was required for scanning (10,11), which is the primary reason to reduce the injection time of the contrast agent. However, a low concentration and volume of the contrast agent were used for CTA, resulting in a decreasing trend in the time density curve (TDC), which affected the arterial enhancement.…”

Section: Discussionmentioning

confidence: 90%

“…Coronary arterial motion is intense and complicated (24); following the high temporal resolution, DSCT can offer assessable image quality without motion artifacts within a single cardiac cycle (25). Based on the width of several cardiac cycles prior to acquisition, high-pitch scanning requires a suitable acquisition time in order to prospectively predict the correct trigger exposure (10). Calculations revealed that the CTA requires two cardiac cycles for imaging.…”

Section: Discussionmentioning

confidence: 99%

“…High temporal resolution can also maintain or improve image quality for CT coronary angiography (CTCA) (8,9). In previous studies, cardiovascular and cerebrovascular imaging has utilized the 128-slice DSCT, obtaining a reliable image quality with a low-dose length product (DLP; 224.83–256.30 mGy·cm) and contrast agent (60–80 ml) (10,11). However, these studies were conservative with a high tube voltage (100 or 120 kV) and high concentration contrast agent (370 mg/ml), and did not utilize the advantages of 128-slice DSCT, particularly by combining the iterative algorithm and ultra-low tube voltage to reduce the radiation dose for the patients of standard body type.…”

Section: Introductionmentioning

confidence: 99%

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Ultra‑low dose one‑step CT angiography for coronary, carotid and cerebral arteries using 128‑slice dual‑source CT: A feasibility study

et al. 2019

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Atherosclerotic diseases are systemic and patient outcomes depend on comprehensive imaging evaluation. Computed tomography angiography (CTA) is a powerful tool used to assess atherosclerosis. However, the scanning protocol is designed for cardiovascular and cerebrovascular imaging, which require considerations into the radiation dose, contrast agent and image quality. The purpose of the present study was to evaluate ultra-low dose one-step CTA for coronary, carotid and cerebral arteries with a low concentration contrast agent. A total of 78 patients were enrolled and randomly divided into two groups: Group A (n=38) and B (n=40). High-pitch CTA for coronary, carotid and cerebral arteries with a tube voltage of 70 or 80 kVp and 40 ml contrast agent (270 mgI/ml) was performed by a 128-slice dual-source CT scanner for group A. Standard high-pitch CTA with a tube voltage of 100 kVp and 60 ml contrast agent (370 mgI/ml) was conducted for group B. The image quality, radiation dose and amount of contrast agent in group A were evaluated and compared with group B. The dose length product for groups A and B was 62.95±21.54 vs. 160.15±15.13 mGy cm, respectively (t=−23.157, P<0.001). The mean total iodine content was 10.8±0 mg for group A and 22.2±0 mg for group B. In total, 99.4% of the arterial segments could be assessed for the two groups ( χ 2 =0.267, P=0.606). The results revealed that ultra-low dose one-step high-pitch CTA can provide assessable image quality, and minimize the radiation dose and contrast agent.

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Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ultra‑low dose one‑step CT angiography for coronary, carotid and cerebral arteries using 128‑slice dual‑source CT: A feasibility study

et al. 2019

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Non-contrast-enhanced MR-angiography of Extracranial Arteries in Acute Ischemic Stroke at 1.5 Tesla Using Relaxation-Enhanced Angiography Without Contrast and Triggering (REACT)

Janssen,

Rose,

Kaya

et al. 2024

Clin Neuroradiol

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Purpose To evaluate a novel flow-independent sequence (Relaxation-Enhanced Angiography without Contrast and Triggering (REACT)) for imaging of the extracranial arteries in acute ischemic stroke (AIS) at 1.5 T. Methods This retrospective single-center study included 47 AIS patients who received REACT (scan time: 3:01 min) and contrast-enhanced MRA (CE-MRA) of the extracranial arteries at 1.5 T in clinical routine. Two radiologists assessed scans for proximal internal carotid artery (ICA) stenosis, stated their diagnostic confidence and rated the image quality of cervical arteries, impact of artifacts and image noise. Apparent signal- and contrast-to-noise ratios (aSNR/aCNR) were measured for the common carotid artery and ICA. Results REACT achieved a sensitivity of 95.0% and a specificity of 97.3% for ICA stenoses in high agreement with CE-MRA (κ = 0.83) with equal diagnostic confidence (p = 0.22). Image quality was rated higher for CE-MRA at the aortic arch (p = 0.002) and vertebral arteries (p < 0.001), whereas REACT provided superior results for the extracranial ICA (p = 0.008). Both sequences were only slightly affected by artifacts (p = 0.60), while image noise was more pronounced in CE-MRA (p < 0.001) in line with higher aSNR (p < 0.001) and aCNR (p < 0.001) values in REACT for all vessels. Conclusion Given its good diagnostic performance while yielding comparable image quality and scan time to CE-MRA, REACT may be suitable for the imaging of the extracranial arteries in acute ischemic stroke at 1.5 T.

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Automated estimation of image quality for coronary computed tomographic angiography using machine learning

et al. 2018

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Evaluation of high-pitch dual-source CT angiography for evaluation of coronary and carotid-cerebrovascular arteries

Cited by 12 publications

References 33 publications

Ultra‑low dose one‑step CT angiography for coronary, carotid and cerebral arteries using 128‑slice dual‑source CT: A feasibility study

Ultra‑low dose one‑step CT angiography for coronary, carotid and cerebral arteries using 128‑slice dual‑source CT: A feasibility study

Non-contrast-enhanced MR-angiography of Extracranial Arteries in Acute Ischemic Stroke at 1.5 Tesla Using Relaxation-Enhanced Angiography Without Contrast and Triggering (REACT)

Automated estimation of image quality for coronary computed tomographic angiography using machine learning

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