2015
DOI: 10.5455/2319-2003.ijbcp20150230
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Evaluation of hepatoprotective activity of Boerhaavia diffusa against carbon tetrachloride induced liver toxicity in albino rats

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Cited by 4 publications
(2 citation statements)
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“…Finally, the presence of three herbal components also produced a possible synergistic effect in ameliorating CCl 4 induced hepatic injury that needs to be explored further. The dose of individual plant extract applied at the highest tested dose of SKK (200 mg/kg) was relatively low as compared to several other published studies using individual plant extracts of B. diffusa L. , P. niruri L., and S. nigrum L. for hepatoprotection in CCl 4 stimulated murine models (Chandan et al, 1991;Manjrekar et al, 2008;Beedimani and Jeevangi, 2017;Krithika and Verma, 2019).…”
Section: Discussionmentioning
confidence: 86%
“…Finally, the presence of three herbal components also produced a possible synergistic effect in ameliorating CCl 4 induced hepatic injury that needs to be explored further. The dose of individual plant extract applied at the highest tested dose of SKK (200 mg/kg) was relatively low as compared to several other published studies using individual plant extracts of B. diffusa L. , P. niruri L., and S. nigrum L. for hepatoprotection in CCl 4 stimulated murine models (Chandan et al, 1991;Manjrekar et al, 2008;Beedimani and Jeevangi, 2017;Krithika and Verma, 2019).…”
Section: Discussionmentioning
confidence: 86%
“…Liver is the most important key organ in the metabolism, detoxification and secretory functions in the body and it is highly affected primarily by toxic agents that why we studied the following parameters which are found to be of great importance in the assessment of liver damage. Aspartate aminotransferase (AST) enzyme, Alanine aminotransferase (ALT) enzyme, Total protein (T.P), Albumin (Alb) and Bilirubin is found mainly in the liver, but also found in red blood cells, heart cells, muscle tissue and other organs, such as the pancreas and kidneys [42]. Bilirubin, another substance commonly measured in the blood to detect liver disease, is produced from the breakdown of red blood cells.…”
Section: Variablementioning
confidence: 99%