Evaluation of heated humidifiers for use on intubated patients: a comparative study of humidifying efficiency, flow resistance, and alarm functions using a lung model

Rathgeber, Jörg; Kazmaier, S.; Penack, Olaf; Züchner, K.

doi:10.1007/s00134-002-1275-9

Cited by 23 publications

(13 citation statements)

References 22 publications

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“…Indeed, when considering independent evaluations, the best-performing HMEs provide a level of 30 mg H 2 O/L or slightly above 21 and heated wire HHs provide a level of 36 mg H 2 O/L within optimal conditions of utilization. 10,32 The hygrometric levels reached with the maximal minute ventilation (30 L/min), approaching 44 mg H 2 O/L, could eventually lead to overhumidification. For all of these reasons, the clinical indication of active HMEs remains unclear.…”

Section: Discussionmentioning

confidence: 99%

Influence of Ambient Temperature and Minute Ventilation on Passive and Active Heat and Moisture Exchangers

et al. 2013

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OBJECTIVE: During invasive mechanical ventilation, inspired gases must be humidified. We previously showed that high ambient temperature greatly impaired the hygrometric performance of heated wire-heated humidifiers. The aim of this bench and clinical study was to assess the humidification performance of passive and active heat and moisture exchangers (HMEs) and the impact of ambient temperature and ventilator settings. METHODS: We first tested on the bench a device with passive and active humidification properties (Humid-Heat, Teleflex), and 2 passive hydrophobic/hygroscopic HMEs (Hygrobac and Hygrobac S, Tyco Healthcare). The devices were tested at 3 different ambient temperatures (from 22 to 30°C), and at 2 minute ventilation settings (10 and 20 L/min). Inspired gas hygrometry was measured at the Y-piece with the psychrometric method. In addition to the bench study, we measured the hygrometry of inspired gases in 2 different clinical studies. In 15 mechanically ventilated patients, we evaluated Humid-Heat at different settings. Additionally, we evaluated Humid-Heat and compared it with Hygrobac in a crossover study in 10 patients. RESULTS: On the bench, with the Hygrobac and Hygrobac S the inspired absolute humidity was ϳ30 mg H 2 O/L, and with the Humid-Heat, slightly < 35 mg H 2 O/L. Ambient temperature and minute ventilation did not have a clinically important difference on the performance of the tested devices. During the clinical evaluation, Humid-Heat provided inspired humidity in a range from 28.5 to 42.0 mg H 2 O/L, depending on settings, and was only weakly influenced by the patient's body temperature. CONCLUSIONS: In this study both passive and active HMEs had stable humidification performance with negligible influence of ambient temperature and minute ventilation. This contrasts with previous findings with heated wire-heated humidifiers. Although there are no clear data demonstrating that higher humidification impacts outcomes, it is worth noting that humidity was significantly higher with the active HME.

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Section: Discussionmentioning

confidence: 99%

Influence of Ambient Temperature and Minute Ventilation on Passive and Active Heat and Moisture Exchangers

et al. 2013

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“…Die Wasserbindungskapazität kann durch Imprägnieren des Filtermediums mit hygroskopischen Substanzen deutlich gesteigert werden. Hygroskopische HMEF sind in der Befeuchtungsleistung Aktivbefeuchtern gleichwertig [24]. Da der HMEF nicht die gesamte Wärme und Feuchtigkeit aufnehmen und zurückge-ben kann, entsteht in Abhängigkeit von der Qualität des HMEF und dem Beatmungsmuster ein Wasserverlust.…”

Section: Passive Befeuchtungunclassified

Einfluss von aktiver und passiver Befeuchtung auf die beatmungsassoziierte nosokomiale Pneumonie

et al. 2004

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“…However, limitations of the uncontrolled nature of HFNC delivery of NCPAP have not been adequately studied beyond the premature neonate. Vapotherm (VPT) 2000i (Vapotherm, Stevensville, MD) and FisherPaykel (F&P) (Fisher and Paykel Health Care, Auckland, New Zealand) are two commercially available HFNC devices that deliver breathing gases heated to near-body temperature and highly saturated with water vapor, through nasal cannulas at a relatively high flow rates (1-40 L/min) (2,6,7).…”

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confidence: 99%

Effects of flow rate and airleak at the nares and mouth opening on positive distending pressure delivery using commercially available high-flow nasal cannula systems: A lung model study

Hasan

Habib

2011

Pediatric Critical Care Medicine

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Evaluation of heated humidifiers for use on intubated patients: a comparative study of humidifying efficiency, flow resistance, and alarm functions using a lung model

Cited by 23 publications

References 22 publications

Influence of Ambient Temperature and Minute Ventilation on Passive and Active Heat and Moisture Exchangers

Influence of Ambient Temperature and Minute Ventilation on Passive and Active Heat and Moisture Exchangers

Einfluss von aktiver und passiver Befeuchtung auf die beatmungsassoziierte nosokomiale Pneumonie

Effects of flow rate and airleak at the nares and mouth opening on positive distending pressure delivery using commercially available high-flow nasal cannula systems: A lung model study

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