Evaluation of hair loss

Sperling, Leonard C.

doi:10.1016/s1040-0486(96)80003-2

Cited by 23 publications

(21 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a study by Sperling, 1996, an excess of vellus follicles were found in the superficial dermis compared to the deep dermis, what could explain the discrepancies. 7 In both groups assessed, over 90% of follicles observed were terminal (92.0% in Group 1 and 90.1% in Group 2), which is compatible with normal scalp. Vellus follicle bulbs are located in the dermis, many of which in are in its superficial region.…”

Section: Discussionmentioning

confidence: 95%

“…16 Whiting, in 1996, and Steiner, in 1988, found a T/V ratio of 7:1 in rather superficial slices. 7,13 Hair growth cycle causes continuous follicular changes. Histological assessment of hair growth cycles is done by the observation of the follicular structure changes.…”

Section: Discussionmentioning

confidence: 99%

“…Early cross-sectional studies demonstrated 12 a 14 follicular units per sample. 3,7,14 This difference may be explained by the different populations assessed and depth of the section. In one of these studies, the depth is not described and in another the superficial dermis was assessed.…”

Section: This Study Was Carried Out At the Instituto De Medicina Legamentioning

confidence: 99%

See 2 more Smart Citations

Avaliação quantitativa em cortes histológicos transversais do couro cabeludo

Mulinari‐Brenner

Souza

Neto

et al. 2006

An. Bras. Dermatol.

View full text Add to dashboard Cite

BACKGROUND -Punch-biopsy is a great tool for the diagnosis of scalp disorders, however experience is required for the dermatopathologist. Recognizing the standard structures found in normal scalp is very helpful in this aspect. OBJECTIVE -The goal of this study was to determine quantitative data considering normal structures on the scalp of white adults. METHODS -Twenty necropsies were followed by eighty 4mm-punch biopsies of clinically normal scalp. Samples were evaluated by transverse sections. RESULTS -Scalp fragments from white adults, age 21 to 78, demonstrated (medians): 16.5 (12.0-23.0) total follicles; 8.0 (6.0-9.0) follicular units; 15.0 (10.0-20.0) terminal follicles; 1.0 (0.0-2.0) vellus follicle; and 1.0 (0.0-2.5) fibrous tract. Considering the hair cycle phase: 92.2% were in anagen; 1.6% in catagen and 6.2% in telogen. CONCLUSION -Comparing the results, male samples demonstrated fewer follicular units, total and telogen follicles, and higher number of total follicles and fibrous tracts on frontal and vertex area. Keywords: Alopecia; Dermatology; Hair follicle; Histology; Scalp 16,5 (12-23) folículos totais; oito (6-9) unidades foliculares; 15 (10-20) folículos terminais; um (0-2) folículo velo; um (0-2,5) Resumo: FUNDAMENTOS -A biópsia por punch é de grande auxílio no diagnóstico das doenças do couro cabeludo quando avaliada por patologista experiente. O conhecimento das estruturas encontradas no couro cabeludo normal facilita o diagnóstico histopatológico nessa área tão complexa da dermatopatologia. OBJETIVO -Determinar dados quantitativos normais do couro cabeludo de adultos brancos. MÉTODOS -Em 20 necrópsias, 80 fragmentos de couro cabeludo clinicamente normal foram obtidos por punch 4mm. As amostras foram avaliadas em cortes transversais. RESULTADOS -Em fragmentos obtidos de adultos brancos, com idade variando entre 21 e 78 anos, foi possível observar (medianas):

show abstract

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Avaliação quantitativa em cortes histológicos transversais do couro cabeludo

Mulinari‐Brenner

Souza

Neto

et al. 2006

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

“…3,5,7 Conical specimens show a reduced number of terminal anagen bulbs, which interferes with the assessment.…”

Section: Discussionmentioning

confidence: 99%

Morfometria de folículos pilosos do couro cabeludo normal

Mulinari‐Brenner

Rosas

Neto

et al. 2006

An. Bras. Dermatol.

View full text Add to dashboard Cite

BACKGROUND -Histological description of normal human hair follicle has scarce literature. Recognizing normal scalp follicle and its variability throughout the scalp is fundamental to study scalp disorders. OBJECTIVES -To evaluate normal scalp samples in Caucasians considering cross-section area, maximum and minimum diameters of terminal anagen follicles. METHODS -Twenty necropsies of Caucasian individuals (10M, 10F) were followed by a 4mm punch biopsy of 4 scalp areas. Transverse sections were evaluated by light microscopy. Terminal anagen follicle cross-section area, maximum and minimum diameters were determined by computer image analysis. Results were compared between sexes and scalp areas. RESULTS -Follicular area and maximum and minimum diameters are presented. CONCLUSION -No statistically significant differences were observed in follicular maximum diameter and area in several scalp regions. However, the morphometric evaluation of terminal anagen follicles demonstrated greater dimensions within the male group. Keywords: Alopecia; Hair; Hair follicle; Histology Resumo: FUNDAMENTOS -A caracterização histológica do folículo piloso normal em humanos é escassa na literatura, considerando que o reconhecimento da arquitetura folicular normal e suas variações nas diversas áreas do couro cabeludo é fundamental para o estudo das doenças do couro cabeludo. OBJETIVOS -Analisar fragmentos do couro cabeludo normal em indivíduos de raça branca quanto à área, os diâmetros máximo e mínimo dos folículos anágenos terminais. MÉTODOS -Vinte necrópsias de indivíduos de raça branca

show abstract

“…2 We also know of no reports of TTA associated with other scalp disorders. 4 Histopathologically, TTA is characterized by an absence of inflammation and a normal number of hairs that are all miniaturized. 2,4 The abnormal histologic condition of this lesion is best evaluated by transverse section, where the number and type of hairs can be quantified.…”

Section: Diagnosis and Discussionmentioning

confidence: 99%