Evaluation of Glycemic and Lipid Profile of Offspring of Diabetic Wistar Rats Treated withMalpighia emarginataJuice

Abstract

Knowing that maternal diabetes is related to hyperglycemia and fetal hyperinsulinemia, which affect the lipid metabolism, the aim of this study was to evaluate the effects of Malpighia emarginata (acerola) juice on the glycemic and lipid profile of offspring of diabetic and nondiabetic Wistar rats. The adult offspring of non-diabetic dams and of dams with severe streptozotocin-induced diabetes were divided into groups: G1, offspring (of control dams) treated with water, G2, offspring (of diabetic dams) treated with water, G3, male offspring (of control dams) treated with acerola juice, and G4, male offspring (of diabetic dams) treated with acerola juice. The offspring of diabetic dams treated with acerola juice showed significantly decreased levels of glucose, cholesterol, triglycerides, and increased HDL-c. The use of acerola juice is a potential strategy to aid in the prevention of DM and dyslipidemia and its complications or to act as an auxiliary in the treatment of these diseases.

Effects ofPassiflora edulis(Yellow Passion) on Serum Lipids and Oxidative Stress Status of Wistar Rats

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Effects of <i>Pereskia aculeata</i> Miller on the Biochemical Profiles and Body Composition of Wistar Rats

“…Plant-based medicines have become increasingly popular for the treatment of several disorders for several reasons, including their cost, which is lower than that of traditional allopathic medicines. Thus, many studies have focused on evaluating the actual effect of medicinal plants in promoting health or preventing risk factors for several diseases, such as dyslipidemias, hypertension, diabetes, metabolic syndrome and cardiovascular diseases [1] [2]. These disorders are associated with high levels of body fat caused by a diet rich in saturated fats and sugar, changes in lifestyle and physical inactivity [3]- [8].…”

Evaluation of antioxidant potential of Emblica officinalis and Murraya koenigii and their role in modulation of cognitive function in diabetic rats

“…Our results are in accordance with previous studies. 20,21 Transfer latency on elevated plus maze, step-down latency on passive avoidance apparatus and spatial navigation task in Morris-water maze were used to assess the behavioural parameters of learning and memory. Brain levels of MDA and GSH were measured as an analysis of oxidative stress and AChE levels in brain were measured as the biochemical parameter of cognition and memory.…”