Evaluation of gastro-oesophageal reflux disease in wheezy infants using 24-h oesophageal combined impedance and pH monitoring

Multichannel intraluminal impedance-pH and psychometric properties in gastroesophageal reflux: systematic review

“…The analyzed studies demonstrated sensitivity values considered to be high: 76.1% to 80.3% in Rosen et al, 16 100% in Blasco-Alonso et al, 20 73% in Lau et al, 21 87.2% in Kilzilkan, 22 and 77% in Abdallah, 23 whereas specificity values were of 23% in Kilzilkan et al, 22 25% in Blasco-Alonso et al, 20 and only Abdallah et al 23 presented values of 80%.…”

“…Regarding study designs, most of them were prospective. 17 , 18 , 19 , 22 , 23 Among the main PP, sensitivity was verified in six studies, 16 , 18 , 20 , 21 , 22 , 23 in which four associated specificity assessment. 18 , 19 , 20 , 22 , 23 Variances of accuracy 19 and reproducibility 17 were also noted.…”

“…The characteristics of the selected studies are described in Table 2 , in which different nationalities were observed: two Americans, 16 , 18 three Europeans, 17 , 19 , 20 one Asian, 21 one Euro-Asian, 22 and one African. 23 The oldest study found was by Rosen et al 16 in 2006. Regarding study designs, most of them were prospective.…”

“…According to the PRISMA recommendations, 15 two evaluators performed the extraction and analysis of the selected articles. Data on authorship, year of publication, nationality, study design, population studied, sample size, gender, age group, and PP were extracted from the selected studies 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ( Table 2 ). Table 3 presents the objectives of these studies, 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 the results of the MIIpH in relation to the psychometric property evaluated, and its conclusion.…”

“… No or slight agreement was found between pHmetry, MII, MIIpH and GES for diagnosis of GERD. Abdallah et al, 2017 23 1. Determine the GERD prevalence using MIIpH versus pHmetry.…”