Evaluation of Free Radical Scavenging, Anti-inflammatory and Analgesic Potential of Benincasa hispida Seed Extract

Gill, N.S.; Dhiman, Kunal; Bajwa, Jasveen; Sharma, PD; Sood, Shailja

doi:10.3923/ijp.2010.652.657

Cited by 41 publications

(20 citation statements)

References 22 publications

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“…In addition, other phytochemical constituents reported in Kundur fruit reveal the presence of triterpenes (alnusenol, multiflorenol, isomultiflorenol), sterols (lupeol, lupeol acetate, β-sitosterol), glycosides, saccharides, carotenes, β-sitosterin, tannins and uronic acid (Gill, Dhiman, Bajwa, Sharma, & Sood, 2010;Wollenweber, Faure, & Gaydou, 1991;Yoshizumi et al, 1998). Among the active triterpenes and sterols, two triterpenes, alnusenol and multiflorenol, have the ability to potently inhibit the histamine release (Yoshizumi et al, 1998).…”

Section: Miscellaneous Compoundsmentioning

confidence: 97%

“…Chandrababu and Umamaheshwari (2002) and studied the anti-inflammatory properties of Kundur fruit rind and fruit juices, respectively. Gill et al (2010) suggested that free radical scavenging activity of Kundur fruit seed might have been responsible for the reduction of inflammation in the carrageenan-induced paw edema in rats (Cuzzocrea, Riley, Caputi, & Salvemini, 2001). The anti-inflammatory effects of Kundur fruit might be related to the presence of bioactive terpenoids (Shetty et al, 2008).…”

Section: Alzheimer Disease Treatmentmentioning

confidence: 97%

“…5.6. Anti-inflammatory Gill et al (2010) investigated the anti-inflammatory effects of Kundur fruit seed. Chandrababu and Umamaheshwari (2002) and studied the anti-inflammatory properties of Kundur fruit rind and fruit juices, respectively.…”

Section: Alzheimer Disease Treatmentmentioning

confidence: 99%

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Kundur [Benincasa hispida (Thunb.) Cogn.]: A potential source for valuable nutrients and functional foods

Zaini

Anwar

Hamid

et al. 2011

Food Research International

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Section: Miscellaneous Compoundsmentioning

confidence: 97%

Section: Alzheimer Disease Treatmentmentioning

confidence: 97%

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Kundur [Benincasa hispida (Thunb.) Cogn.]: A potential source for valuable nutrients and functional foods

Zaini

Anwar

Hamid

et al. 2011

Food Research International

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“…Ash gourd (Benincasa hispida) is an annular trailing or climbing herb and is cultivated widely in India. In Ayurveda, it is recommended for treating peptic ulcer, urinary tract infections, diabetes mellitus, epilepsy and other nervous system disorders (Gill et al 2010;Palamthodi and Lele 2014). Further, ash gourd is proved to have an excellent prebiotic activity (Sreenivas and Lele 2013).…”

Section: Introductionmentioning

confidence: 99%

Physicochemical and functional properties of ash gourd/bottle gourd beverages blended with jamun

2018

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This paper reports the formulation and storage stability of Ash gourd (Benincasa hispida) and Bottle gourd (Lagenaria siceraria) juice blended with the Jamun (Syzygium cumini). Both the beverages found to be rich in polyphenols, flavonoids, and anthocyanins. The Ash gourd-Jamun (AGJ) and Bottle gourd-Jamun (BGJ) beverages showed significant bio-accessibility of polyphenols, flavonoids, and anthocyanins. Moreover, the addition of sugar was found to enhance the bioaccessibility of these fractions in both the beverages. Further, the biochemical attributes such as physiochemical and functional properties of Ash gourd-Jamun and Bottle gourd-Jamun blended juice were evaluated during the accelerated storage. The total soluble solids and acidity and the sensory score did not change significantly during the storage period. The AGJ exhibited a 35%, 73%, 34% and 35%, whereas BGJ shows 32%, 65%, 35% and 20% decrease in total polyphenol, anthocyanin, DPPH and inflammatory activity during the 2 months of storage period respectively. However, the reduction was less in Bottle gourd-Jamun beverage. Results of the study are promising and add to the necessity and potential of gourd family based functional food development.

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“…hispida seeds have long been used as traditional Chinese medicine (TCM) to reduce fevers, eliminate phlegm, discharge pus, and expel dampness, and it has been used in China for the treatment of conditions such as cough accompanied by phlegm and fever, pulmonary abscesses, periappendicular abscesses, gonorrhea, spermatorrhea, and edema [1,2]. Modern studies have demonstrated that many pharmacological effects, including anti-inflammatory, analgesic, antioxidant, antiangiogenic, and antidiabetic activities, have been associated with B. hispida seeds [3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

The HPLC Fingerprint and Isovanillin Content ofBenincasa hispidaSeeds

Liu¹,

Li²,

Wang³

et al. 2015

Journal of Chemistry

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TheBenincasa hispidaseed is used as traditional Chinese medicine (TCM). However, there is still a lack of medicinal quality control ofB. hispidaseeds. The seeds may contain isovanillin, but this finding remains to be confirmed and quantified. The current study aimed to confirm the existence of isovanillin and then preliminarily establish medicinal quality standards forB. hispidaseeds. Fourteen batches of unilateral and bilateralB. hispidaseeds were purchased from 7 different producers in China. Semipreparative high-performance liquid chromatography (HPLC) was used to isolate and purify the isovanillin fromB. hispidaseeds. Its chemical structure was elucidated by UV,1H-NMR, IR spectroscopy, and GC-MS. TheB. hispidaseed fingerprint and isovanillin determination were performed on an HPLC instrument. Data obtained from the unilateral and bilateral specimens were analyzed with a similarity evaluation system. The HPLC fingerprint showed 19 characteristic peaks with high similarity between the unilateral and bilateralB. hispidaseeds. The isovanillin content among the fourteen batches ranged from 13.46 to 46.80 μg/g. The results of this study may provide a preliminary reference for the quality control ofB. hispidaseeds.

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Evaluation of Free Radical Scavenging, Anti-inflammatory and Analgesic Potential of Benincasa hispida Seed Extract

Cited by 41 publications

References 22 publications

Kundur [Benincasa hispida (Thunb.) Cogn.]: A potential source for valuable nutrients and functional foods

Kundur [Benincasa hispida (Thunb.) Cogn.]: A potential source for valuable nutrients and functional foods

Physicochemical and functional properties of ash gourd/bottle gourd beverages blended with jamun

The HPLC Fingerprint and Isovanillin Content ofBenincasa hispidaSeeds

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