Evaluation of foot-to-foot bioelectrical impedance analysis for the prediction of total body water in oncology outpatients receiving radiotherapy

Abstract

Objective: To investigate the accuracy of total body water (TBW) predicted by foot-to-foot bioelectrical impedance compared with a deuterium oxide dilution technique in oncology outpatients receiving radiotherapy. Design: Cross-sectional design. Setting: Two private Australian radiation oncology facilities. Subjects: In all, 27 subjects (23 males; four females); mean age 62 (715) y; mean BMI 26.2 kg/m 2 (73.6). Intervention: TBW was measured using a deuterium oxide dilution technique and predicted using foot-to-foot bioelectrical impedance (Tanita Inc., Tokyo, Japan, Models TBF 410 and 300GS). Results: The mean (s.d.) values for predicted and measured TBW was 41.5 (6.7) and 39.7 (8.7) l, respectively, indicating a mean bias to overestimation by the foot-to-foot impedance of 1.8 l. However, a significant negative correlation between the mean of the measurements of TBW and their difference (r ¼ À0.40; P ¼ 0.04) indicates a progressive underestimation of TBW by foot-tofoot impedance as the water content of the body increases. The analysis of 95% limits of agreement (72 s.d.) showed that for most individuals the TBW predicted by foot-to-foot impedance can vary as much as 12 l above or 8.6 l below the actual TBW measured by a deuterium oxide dilution technique. Conclusion: There is good agreement between foot-to-foot bioelectrical impedance with a gold standard technique at the group level. However, the significant correlation between the difference of predicted and measured TBW, and the wide limits of agreement between the two methods, indicates that the use of foot-to-foot impedance in assessing TBW may lead to unacceptable error in individuals.

The agreement between measured and predicted resting energy expenditure in patients with pancreatic cancer — A pilot study

“…In this study the best combination of low bias and narrow limits of agreement was observed in the prediction of REE from the Wang equation based on FFM. Measurement of FFM using the deuterium dilution technique is impractical in the clinical setting, and other methods such as bioelectrical impedance analysis have been shown to be inaccurate at prediction of FFM at the individual level in patients with cancer [38]. Therefore, most clinicians rely on REE prediction equations that incorporate easily measurable variables, such as body weight and height.…”

Nutrition intervention is beneficial in oncology outpatients receiving radiotherapy to the gastrointestinal or head and neck area

“…We have previously shown that footto-foot BIA is acceptable at the group level in measuring total body water and, hence FFM, in oncology patients receiving radiotherapy (Isenring et al, 2004).…”

Bioelectrical Impedance Phase Angle as a Prognostic Indicator of Survival in Head-and-Neck Cancer

“…Reactance is the resistive effect produced by the tissue interfaces and cell membranes 25 . Thanks to its potential to detect changes in tissue electrical properties, pa has been found to be an indicator for cell membrane integrity, distribution of water between the intracellular and extracellular spaces, and prediction of body cell mass in various disease conditions [26][27][28][29][30][31][32][33][34] .…”