Evaluation of ferrofluid-coated rotating magnetic field-assisted bioreactor for biomass production

Jabłońska, Joanna; Augustyniak, Adrian; Kordas, Marian; Dubrowska, Kamila; Sołoducha, Dawid; Borowski, Tomasz; Konopacki, Maciej; Grygorcewicz, Bartłomiej; Roszak, Marta; Dołęgowska, Barbara; Piz, Mateusz; Filipek, E.; Wróbel, Rafał; Leniec, Grzegorz; Rakoczy, Rafał

doi:10.1016/j.cej.2021.133913

Cited by 11 publications

(7 citation statements)

References 55 publications

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“…As already mentioned, the strength of magnetic field impact (regardless of its type or the phenomenon analyzed in its presence), except for the exposure duration, depends on its intensity and/or frequency 17 , 28 , 44 , 46 , because these two factors determine the physical characteristics of the magnetic signal 47 , 48 . In the case of the RMF setup used in the present study, the magnetic field is axially symmetric and magnetic field lines rotate in a horizontal direction, with the rotation frequency equal to the frequency of the electric current 49 . Therefore, depending on the applied electric current frequencies, also the synchronous speed of the magnetic flux rotation around the stator is different, as can be seen in the simulations: 5 Hz— https://www.youtube.com/watch?v=EwojY3mR11A ; 50 Hz— https://www.youtube.com/watch?v=swCPxvRdZoc .…”

Section: Discussionmentioning

confidence: 99%

The effects of rotating magnetic field and antiseptic on in vitro pathogenic biofilm and its milieu

Ciecholewska-Juśko

Żywicka

Junka

et al. 2022

Sci Rep

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The application of various magnetic fields for boosting the efficacy of different antimicrobial molecules or in the character of a self-reliant antimicrobial agent is considered a promising approach to eradicating bacterial biofilm-related infections. The purpose of this study was to analyze the phenomenon of increased activity of octenidine dihydrochloride-based antiseptic (OCT) against Staphylococcus aureus and Pseudomonas aeruginosa biofilms in the presence of the rotating magnetic field (RMF) of two frequencies, 5 and 50 Hz, in the in vitro model consisting of stacked agar discs, placed in increasing distance from the source of the antiseptic solution. The biofilm-forming cells' viability and morphology as well as biofilm matrix structure and composition were analyzed. Also, octenidine dihydrochloride permeability through biofilm and porous agar obstacles was determined for the RMF-exposed versus unexposed settings. The exposure to RMF or OCT apart did not lead to biofilm destruction, contrary to the setting in which these two agents were used together. The performed analyses revealed the effect of RMF not only on biofilms (weakening of cell wall/membranes, disturbed morphology of cells, altered biofilm matrix porosity, and composition) but also on its milieu (altered penetrability of octenidine dihydrochloride through biofilm/agar obstacles). Our results suggest that the combination of RMF and OCT can be particularly promising in eradicating biofilms located in such areas as wound pockets, where physical obstacles limit antiseptic activity.

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Section: Discussionmentioning

confidence: 99%

The effects of rotating magnetic field and antiseptic on in vitro pathogenic biofilm and its milieu

Ciecholewska-Juśko

Żywicka

Junka

et al. 2022

Sci Rep

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“…Notably, maximal induction values were observed at the midpoint of the RMF generator height, measuring 42.64 mT for a frequency of 50 Hz. Full characteristics of the research system used were described earlier by Jabło ńska et al [79].…”

Section: Methods Of Determination Of Platelet Growth Factorsmentioning

confidence: 99%

The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets

Cecerska-Heryć,

Goszka,

Gliźniewicz

et al. 2024

IJMS

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Platelets are actively involved in tissue injury site regeneration by producing a wide spectrum of platelet-derived growth factors such as PDGF (platelet-derived growth factor), IGF-1 (insulin-like growth factor), TGF-β1 (transforming growth factor β), FGF (fibroblast growth factor), etc. A rotating magnetic field (RMF) can regulate biological functions, including reduction or induction regarding inflammatory processes, cell differentiation, and gene expression, to determine the effect of an RMF on the regenerative potential of platelets. The study group consisted of 30 healthy female and male volunteers (n = 15), from which plasma was collected. A portion of the plasma was extracted and treated as an internal control group. Subsequent doses of plasma were exposed to RMF at different frequencies (25 and 50 Hz) for 1 and 3 h. Then, the concentrations of growth factors (IGF-1, PDGF-BB, TGF-β1, and FGF-1) were determined in the obtained material by the ELISA method. There were statistically significant differences in the PDGF-BB, TGF-β1, IGF-1, and FGF-1 concentrations between the analyzed groups. The highest concentration of PDGF-BB was observed in the samples placed in RMF for 1 h at 25 Hz. For TGF-β1, the highest concentrations were obtained in the samples exposed to RMF for 3 h at 25 Hz and 1 h at 50 Hz. The highest concentrations of IGF-1 and FGF-1 were shown in plasma placed in RMF for 3 h at 25 Hz. An RMF may increase the regenerative potential of platelets. It was noted that female platelets may respond more strongly to RMF than male platelets.

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“…The same pulsatory rotating magnetic field or a sinusoidal rotating magnetic field obtained from an induction motor could be applied to bioreactors used for biomass production [15]. A bacterial culture sample was coated with a magnetic nanofluid inserted in a special beaker wall, and a much more positive bacteria growth rate was observed.…”

Section: Applicationsmentioning

confidence: 99%

Microactuation of Magnetic Nanofluid Enabled by a Pulsatory Rotating Magnetic Field

Pîslaru‐Dănescu

Zărnescu

Patroi³

et al. 2023

Actuators

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A microactuation process was developed with the help of four coils that generate a pulsatory rotating magnetic field. A small actuator stator, which contains a 46 mm acrylonitrile butadiene styrene (ABS) opened box and four coils with E-type ferrite cores, was constructed. Simulations were made for different Duty Cycles, 0.2, 0.5, 0.72 and 0.9, and distances above the E cores, between 0.01 and 6 mm. These simulations determined the magnetic bubble inflating distance, the saturation regions and the average forces that are responsible for nanofluid flow inside the ABS box. An electrical driving scheme was designed, and a drive was constructed to activate four inductive loads that generate a pulsatory rotating magnetic field. The electronic drive can change the actuation frequency (rotation speed) between 1 Hz and 25 Hz and can adjust the Duty Cycle between 5% and 95% (driving force). From simulations and experiments, it was observed that the Duty Cycle must be limited to 0.7 to avoid the magnetic nanofluid saturation at 45 mT. It was found that three applications use a pulsatory rotating magnetic field: a small motor, a small flat pump and a manipulating sheet matrix for displays or chemical droplets mixing.

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Evaluation of ferrofluid-coated rotating magnetic field-assisted bioreactor for biomass production

Cited by 11 publications

References 55 publications

The effects of rotating magnetic field and antiseptic on in vitro pathogenic biofilm and its milieu

The effects of rotating magnetic field and antiseptic on in vitro pathogenic biofilm and its milieu

The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets

Microactuation of Magnetic Nanofluid Enabled by a Pulsatory Rotating Magnetic Field

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